用于导管相关尿路感染早期风险检测的贴纸式远程监测系统
Sticker-Type Remote Monitoring System for Early Risk Detection of Catheter Associated Urinary Tract Infections.
作者信息
Gopalakrishnan Sarath, Rana Muhammad Masud, Curry Michael Anthony, Krishnakumar Akshay, Rahimi Rahim
出版信息
IEEE Trans Biomed Eng. 2024 Jul;71(7):2070-2079. doi: 10.1109/TBME.2024.3361439. Epub 2024 Jun 19.
A substantial number of critically ill patients in intensive care units (ICUs) rely on indwelling urinary catheters (IDCs), demanding regular monitoring of urine bags. This process increases the workload for healthcare providers and elevates the risk of exposure to contagious diseases. Moreover, IDCs are a primary cause of catheter-associated urinary tract infections (UTIs) in ICU patients whose delayed detection can have life-threatening complications. To address this, we have developed a Sticker Type Antenna for Remote Sensing (STARS) system capable of measuring urine flow rate and conductivity as early-risk markers for UTIs, alongside tracking patients' urine bag status to facilitate medical automation for healthcare providers. STARS comprises a simple, low-cost, disposable antenna module for contactless measurements of urine volume and conductivity, and a reusable wireless module for real-time data transmission. Systematic studies on STARS revealed its stable performance within physiologically relevant ranges of urine volume (0 to 2000 ml) and conductivity (5 to 40 mS/cm) in urine bags. As a proof-of-concept, STARS was tested in artificially created healthy and infected urine specimens to validate its non-contact sensing performance in detecting the onset of UTIs in catheterized patients within a hospital-like environment. STARS represents the first application of a real-time, contactless, wireless monitoring platform for simultaneous urine bag management and early risk detection of UTIs.
重症监护病房(ICU)中有相当数量的重症患者依赖留置尿管(IDC),这就需要定期检查尿袋。这个过程增加了医护人员的工作量,也增加了接触传染病的风险。此外,留置尿管是ICU患者发生导管相关尿路感染(UTI)的主要原因,而UTI的延迟检测可能会导致危及生命的并发症。为了解决这个问题,我们开发了一种用于遥感的贴纸式天线(STARS)系统,该系统能够测量尿流率和电导率,作为UTI的早期风险指标,同时跟踪患者的尿袋状态,以促进医护人员的医疗自动化。STARS包括一个简单、低成本、一次性使用的天线模块,用于非接触式测量尿量和电导率,以及一个可重复使用的无线模块,用于实时数据传输。对STARS的系统研究表明,在尿袋中尿量(0至2000毫升)和电导率(5至40毫西门子/厘米)的生理相关范围内,其性能稳定。作为概念验证,STARS在人工创建的健康和感染尿液样本中进行了测试,以验证其在类似医院环境中检测导尿管患者UTI发病的非接触传感性能。STARS代表了首个用于同时进行尿袋管理和UTI早期风险检测的实时、非接触、无线监测平台。