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夜间支具对青少年特发性脊柱侧凸曲线进展的影响不受曲线幅度的影响:一项 299 例患者的研究。

The influence of night-time bracing on curve progression is not affected by curve magnitude in adolescent idiopathic scoliosis: a study of 299 patients.

机构信息

Spine Unit, Department of Orthopedic Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

出版信息

Acta Orthop. 2024 Feb 12;95:108-113. doi: 10.2340/17453674.2024.39965.

Abstract

BACKGROUND AND PURPOSE

The efficacy of bracing larger curves in adolescent idiopathic scoliosis (AIS) patients is uncertain. We aimed to assess the influence of night-time bracing in AIS patients with main curves exceeding 40° Cobb angle at brace initiation.

METHODS

We reviewed AIS patients treated with nighttime braces between 2005 and 2018. Patients with curves ≥ 25° and estimated growth potential were included. Patients were monitored with radiographs from brace initiation until brace weaning at skeletal maturity. Patients were grouped based on curve magnitude at initial evaluation: a control group (25-39°) and a large-curves group (≥ 40°). Progression was defined as > 5° increase.

RESULTS

We included 299 patients (control group, n = 125; large-curves group, n = 174). In the control group, 65 (52%) patients progressed compared with 101 (58%) in the large-curves group (P = 0.3). The lower-end vertebra (LEV) shifted distally post-bracing in 41 (23%) patients in the largecurves group. Patients with progressive large curves were younger (age 13.2 [SD 1.5] vs. 13.9 [SD 1.1], P = 0.009) and more premenarchal (n = 36 [42%] vs. n = 6 [9%], P < 0.001) compared with non-progressive large curves.

CONCLUSION

Progression risk in patients with curves exceeding 40° treated with night-time bracing is similar to smaller curves. The LEV moved distally in almost one-fourth of the larger curves, possibly affecting fusion levels in cases of surgery.

摘要

背景与目的

支具治疗青少年特发性脊柱侧凸(AIS)患者较大曲度的疗效尚不确定。本研究旨在评估支具初始时主弯 Cobb 角超过 40°的 AIS 患者夜间支具治疗对侧凸进展的影响。

方法

我们回顾了 2005 年至 2018 年期间接受夜间支具治疗的 AIS 患者。纳入主弯角度≥25°且有生长潜能的患者。在支具佩戴开始至骨骼成熟时支具去除期间,通过 X 线片对患者进行监测。根据初始评估时的曲度大小将患者分组:对照组(25-39°)和大弯组(≥40°)。进展定义为增加>5°。

结果

共纳入 299 例患者(对照组 125 例,大弯组 174 例)。对照组中有 65 例(52%)患者进展,大弯组中有 101 例(58%)患者进展(P = 0.3)。大弯组中有 41 例(23%)患者支具治疗后下终椎(LEV)向远端移位。进展性大弯组患者的年龄较小(13.2[标准差 1.5]岁比 13.9[标准差 1.1]岁,P = 0.009),且更多处于青春前期(n = 36[42%]比 n = 6[9%],P < 0.001)。

结论

夜间支具治疗主弯 Cobb 角超过 40°的患者进展风险与较小曲度相似。近四分之一的大弯组患者的 LEV 向远端移位,这可能会影响手术时的融合水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecf6/10863495/8847e0496fe1/ActaO-95-39965-g001.jpg

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