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韩国人群中超薄Descemet膜剥除自动内皮角膜移植术联合白内障手术的一年期疗效

One-year Outcomes of Ultrathin Descemet Stripping Automated Endothelial Keratoplasty Combined with Cataract Surgery in the Korean Population.

作者信息

Koo Minjeong Ashley, Yoon Hye Yeon, Park Jae Hyun, Chung So-Hyang, Kim Hyun-Seung, Byun Yong-Soo

机构信息

Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

Korean J Ophthalmol. 2024 Apr;38(2):105-112. doi: 10.3341/kjo.2023.0101. Epub 2024 Feb 14.

Abstract

PURPOSE

To evaluate the refractive outcomes after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) combined with phacoemulsification and intraocular lens implantation (triple procedure) in the South Korean population.

METHODS

This retrospective observational study included 37 eyes of 36 patients who underwent the UT-DSAEK triple procedure between 2012 and 2021 in a single tertiary hospital. Preoperative and postoperative refractive outcomes and endothelial parameters at 1, 3, 6, and 12 months were observed.

RESULTS

At the final postoperative 12-month period, the average best-corrected visual acuity was 0.4 ± 0.5 in logarithm of the minimum angle of resolution. The mean endothelial cell density at 12 months was 1,841.92 ± 731.24 cells/mm2, indicating no significant endothelial cell loss compared to the baseline (p = 0.128). The mean postoperative central corneal thickness at 12 months was 597.41 ± 86.26 μm. The postoperative mean absolute error at 12 months was 0.96 ± 0.89 diopters (D) and mean error was 0.89 ± 0.97 D.

CONCLUSIONS

The results of our South Korean cohort study on UT-DSAEK triple surgery showed favorable and safe outcomes. Regardless of graft thickness, it should be noted that a hyperopic shift of 1.00 to 2.00 D needs to be considered in the case of UT-DSAEK triple surgery.

摘要

目的

评估超薄Descemet膜剥除自动内皮角膜移植术(UT-DSAEK)联合超声乳化白内障吸除术及人工晶状体植入术(三联手术)在韩国人群中的屈光效果。

方法

这项回顾性观察研究纳入了2012年至2021年期间在一家三级医院接受UT-DSAEK三联手术的36例患者的37只眼。观察术前和术后1、3、6和12个月时的屈光效果及内皮参数。

结果

在术后12个月的最终随访时,平均最佳矫正视力为最小分辨角对数视力表的0.4±0.5。12个月时的平均内皮细胞密度为1,841.92±731.24个细胞/mm²,与基线相比内皮细胞无显著丢失(p = 0.128)。12个月时的术后平均中央角膜厚度为597.41±86.26μm。术后12个月的平均绝对误差为0.96±0.89屈光度(D),平均误差为0.89±0.97 D。

结论

我们对韩国人群进行的UT-DSAEK三联手术队列研究结果显示出良好且安全的效果。无论植片厚度如何,对于UT-DSAEK三联手术,应注意需要考虑1.00至2.00 D的远视性偏移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5e7/11016680/6270748dac64/kjo-2023-0101f1.jpg

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