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[结论而非排除——功能性运动障碍的临床诊断]

[Conclusion instead of exclusion-The clinical diagnosis of functional movement disorders].

作者信息

Weissbach Anne, Bolte Christina, Münchau Alexander

机构信息

Institut für Systemische Motorikforschung, CBBM, Universität zu Lübeck, Marie-Curie-Straße Haus 66, 23562, Lübeck, Deutschland.

出版信息

Nervenarzt. 2024 Jun;95(6):507-515. doi: 10.1007/s00115-024-01613-9. Epub 2024 Feb 14.

Abstract

Functional neurological movement disorders are common in neurological practice and lead to a high degree of impairment and chronification. Affected patients usually receive a diagnosis with considerable delay and often do not get disease-specific treatment. The reasons for this delay are related to extensive diagnostic measures to exclude other nonfunctional neurological diseases. As a consequence, functional movement disorders are typically communicated as diagnoses of exclusion, which makes it difficult for patients to understand and accept the diagnosis. This is particularly unfortunate, because in the majority of patients the diagnosis can be made with confidence based on clinical features, i.e., inconsistency and incongruence. The clarification of the symptoms and the resulting treatment options should be supplemented by patient-friendly explanations of the pathophysiological basis of the disease. In this way, patients are enabled to understand and accept the diagnosis. Moreover, it can put an end to the search for a diagnosis, which can sometimes take decades, and paves the way for treatment. Thus, the diagnosis by exclusion itself becomes the starting point for treatment and can itself have a therapeutic effect.

摘要

功能性神经运动障碍在神经科临床实践中很常见,会导致高度的功能损害和慢性化。受影响的患者通常会被延迟诊断,且往往得不到针对该疾病的治疗。这种延迟的原因与为排除其他非功能性神经疾病而采取的广泛诊断措施有关。因此,功能性运动障碍通常作为排除性诊断传达,这使得患者难以理解和接受该诊断。这尤其不幸,因为在大多数患者中,基于临床特征,即症状的不一致和不协调,能够自信地做出诊断。对症状的澄清以及由此产生的治疗选择,应以对疾病病理生理基础的患者友好型解释作为补充。通过这种方式,患者能够理解并接受诊断。此外,它可以结束有时长达数十年的诊断探索,并为治疗铺平道路。因此,排除性诊断本身就成为治疗的起点,并且其本身就可能具有治疗效果。

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