Gafencu M, Steflea R M
Nephrology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Dialysis, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Acta Endocrinol (Buchar). 2023 Jul-Sep;19(3):403-406. doi: 10.4183/aeb.2023.403. Epub 2024 Feb 1.
Pediatric chronic kidney disease (CKD) has a substantial global impact because is associated with notable morbidity. Secondary hyperparathyroidism (SPHT) frequently emerges as a complication in the early stages of renal insufficiency, it is an adaptive response to uphold mineral balance. It is a component of the chronic kidney disease-mineral and bone disorder (CKD-MBD). The development of SHPT in CKD involves multiple factors and it is important to understand them in order to properly manage it, starting with early diagnosis and continuing with proper treatment. In children with CKD and SHPT, the difficulty in case management is due to non-adherence to proper diet which makes it difficult for the pediatric nephrologist to manage the case. In this review we want to focus on new data regarding this CKD complication.
小儿慢性肾脏病(CKD)在全球具有重大影响,因为它与显著的发病率相关。继发性甲状旁腺功能亢进(SPHT)常作为肾功能不全早期的一种并发症出现,它是维持矿物质平衡的一种适应性反应。它是慢性肾脏病 - 矿物质和骨异常(CKD - MBD)的一个组成部分。CKD中SHPT的发生涉及多个因素,了解这些因素对于妥善管理该疾病很重要,从早期诊断开始并持续进行适当治疗。在患有CKD和SHPT的儿童中,病例管理的困难在于不遵守合理饮食,这使得儿科肾脏病医生难以管理病例。在本综述中,我们希望关注有关这种CKD并发症的新数据。