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结膜黑色素瘤完全治疗后泪道系统和鼻腔黑色素瘤

Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma.

作者信息

Veisi Amirreza, Dastborhan Zahra, Dastmardi Mohsen, Rezaie Kanavi Mozhgan, Rezaei Saeid

机构信息

Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Case Rep Ophthalmol Med. 2024 Feb 8;2024:1034939. doi: 10.1155/2024/1034939. eCollection 2024.

Abstract

Malignant melanoma of the conjunctiva is a rare tumor of the ocular surface with potential fatal consequences and a high likelihood of recurrence. Although routes for extending the tumor, including local, hematogenous, and lymphatogenous, are pretty straightforward, the indirect extension through free-floating tumoral cells to the nasolacrimal duct is not described thoroughly. We report a case of malignant melanoma of the conjunctiva which presented with local recurrence in the intranasal cavity and lacrimal sac two years after the primary surgery (without involvement of the ocular surface and punctum on the second occasion). However, there was no evidence of distant metastasis on either occasion. This case demonstrates the possible noncontiguous spreading route of melanoma tumoral cells and highlights the need for attention to the surgical technique, and careful follow-up to detect further disease activity.

摘要

结膜恶性黑色素瘤是一种罕见的眼表肿瘤,具有潜在的致命后果且复发可能性很高。尽管肿瘤扩展途径,包括局部、血行和淋巴途径都相当明确,但肿瘤细胞通过游离漂浮至鼻泪管的间接扩展尚未得到充分描述。我们报告一例结膜恶性黑色素瘤病例,该病例在初次手术后两年出现鼻腔和泪囊局部复发(第二次复发时眼表和泪点未受累)。然而,两次复发时均无远处转移证据。该病例显示了黑色素瘤肿瘤细胞可能的不连续扩散途径,并强调了需要关注手术技术以及仔细随访以检测进一步的疾病活动情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a415/10869194/e439310dd890/CRIOPM2024-1034939.001.jpg

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