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改良 PATIO 技术治疗尿道下裂术后尿道皮肤瘘:来自一家三级转诊医院的经验。

Modified PATIO technique for urethrocutaneous fistula after hypospadias repair: Experience from a tertiary referral hospital.

机构信息

School of Paediatric Surgery, University of Florence, Florence, Italy; Department of Paediatric Urology, Meyer's Children Hospital IRCCS, Florence, Italy.

Department of Paediatric Urology, Meyer's Children Hospital IRCCS, Florence, Italy.

出版信息

J Pediatr Urol. 2024 Jun;20(3):437.e1-437.e6. doi: 10.1016/j.jpurol.2024.01.031. Epub 2024 Feb 7.

Abstract

INTRODUCTION

Urethrocutaneous fistula (UCF) is a common complication after hypospadias repair with an incidence of 5-10%. Several techniques are described for its repair: small UCFs are frequently corrected by isolation, excision, and closure with apposition of a protective second layer. In 2008 Malone described the PATIO technique: the fistula tract is turned inside out in the urethral lumen preventing contact with passing urine without direct urethral sutures.

OBJECTIVE

Aim of our study is to present our outcomes using a modified version of the PATIO technique, with a more reproducible isolation of the tract and without its fixation at the urethral meatus.

STUDY DESIGN

We retrospectively reviewed all cases of UCFs corrected with a modified PATIO technique at our center between 2016 and 2020. Data collected from electronical clinical notes were age at UCF closure, location of UCF, presence of meatal stenosis and clinical outcomes. Data are presented as median and IQR.

RESULTS

In the study period we performed 425 urethroplasties for distal and mid penile hypospadias. The incidence of UCFs was 7% (30/425) and 25 patients underwent UCF correction with modified PATIO. Median age at repair was 4.5 years (IQR: 2.5-6.2). At a median follow-up of 3 years (IQR: 2-4) recurrence was observed in 5 cases out of 24 with one patient who was lost at follow-up (20.8%). One case was corrected successfully with re-do modified PATIO technique, while 4 are awaiting repair. One cases was lost at follow-up. UFC-recurrence was homogeneously distributed along the study period.

DISCUSSION

Risk factors for UCF recurrence are mostly the type of hypospadias, neo-urethral length, and quality of the urethral plate. Among the many existing techniques, we propose a modified version of Malone's PATIO repair. We believe that the use of four stay-suture to isolate the fistula allows a well-defined dissection of the tract along its surface, compared to the use of a single stay-suture. In our experience, there is no need to keep and fix the traction on the fistula tract to the urethral meatus, probably reflecting the efficacy of the fistula closure during the introflection, which is then maintained without traction. Limitations to our study include the retrospective nature of the review, the small sample size of the cohort and the absence of control groups.

CONCLUSIONS

Our results appear consistent with literature regarding the efficacy of PATIO principles in treating UCF. Modified PATIO seem to be particularly reproducible, showing encouraging results.

摘要

简介

尿道下裂修复术后常发生尿道皮肤瘘(UCF),其发生率为 5-10%。有几种技术可用于修复尿道下裂:对于小的 UCF,常通过隔离、切除和闭合来纠正,并使用第二层保护物进行贴合。2008 年 Malone 描述了 PATIO 技术:将瘘管在尿道腔内翻转,防止尿液接触,而无需直接缝合尿道。

目的

我们的研究旨在介绍使用改良版 PATIO 技术的结果,该技术可更可重复地隔离瘘管,且无需将其固定在尿道口。

研究设计

我们回顾性分析了 2016 年至 2020 年期间在我们中心使用改良版 PATIO 技术矫正 UCF 的所有病例。从电子病历中收集的数据包括 UCF 闭合时的年龄、UCF 的位置、尿道口狭窄的存在和临床结果。数据以中位数和四分位距表示。

结果

在研究期间,我们对 425 例远端和中段阴茎型尿道下裂患者进行了尿道成形术。UCF 的发生率为 7%(30/425),其中 25 例患者接受了改良版 PATIO 治疗。修复时的中位年龄为 4.5 岁(IQR:2.5-6.2)。中位随访 3 年(IQR:2-4)时,24 例中有 5 例复发,其中 1 例失访(20.8%)。1 例患者经再次改良 PATIO 技术成功矫正,4 例仍在等待修复。1 例失访。UCF 复发在整个研究期间均匀分布。

讨论

UCF 复发的危险因素主要是尿道下裂的类型、新尿道的长度和尿道板的质量。在众多现有的技术中,我们提出了改良版 Malone 的 PATIO 修复技术。我们认为,与使用单根缝线相比,使用四根缝线来隔离瘘管可以更明确地沿着瘘管表面进行解剖。根据我们的经验,无需将瘘管的牵引固定在尿道口,这可能反映了在翻转过程中瘘管的闭合效果,然后无需牵引即可保持闭合。我们的研究存在一些局限性,包括回顾性研究设计、队列样本量小以及缺乏对照组。

结论

我们的结果与文献中关于 PATIO 原则治疗 UCF 的疗效一致。改良版 PATIO 似乎特别具有可重复性,结果令人鼓舞。

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