Quéré Baptiste, Saraux Alain, Carvajal-Alegria Guillermo, Guellec Dewi, Mouterde Gaël, Lamotte Christophe, Hammenfors Daniel, Jonsson Malin, Choi Sung-Eun, Hong-Ki Min, Stel Alja, Fisher Benjamin A, Maybury Mark, Hofauer Benedikt, Ferro Francesco, Milic Vera, Direnzo Dana, Devauchelle-Pensec Valérie, Jousse-Joulin Sandrine
Rheumatology Department, CHU Hospital La Cavale-Blanche, Centre National de Référence des Maladies Auto-Immunes Rares (CERAINO), Brest, France.
LBAI, UMR1227, Univ Brest, Inserm, Brest, France.
Rheumatol Ther. 2024 Apr;11(2):411-423. doi: 10.1007/s40744-024-00645-6. Epub 2024 Feb 19.
Major salivary gland ultrasonography (SGUS) demonstrated its good metric properties as an outcome measure for diagnosing primary Sjögren's disease (SD). The objective was to assess SGUS reliability among sonographers with different levels of experience, using web training.
Sonographers from expert centers participated in the reliability exercise. Before exercises, training was done by videoconferencing. Reliability of the two most experienced sonographers (MES) was assessed and then compared to other sonographers. Intra-reader and inter-reader reliability of SGUS items were assessed by computing Cohen's κ coefficients.
All sets were read twice by all 14 sonographers within a 4-month interval. Intra-reader reliability of MES was almost perfect for homogeneity, substantial for Outcome Measures in Rheumatology (OMERACT) scoring system (OMERACTss). Among LES (less experienced sonographers), reliability was moderate to almost perfect for homogeneity, fair to moderate for OMERACTss, and fair to almost perfect for binary OMERACTss. Inter-reader reliability between MES was almost perfect for homogeneity, substantial for diagnosis, moderate for OMERACTss, and substantial for binary OMERACTss. Compared to MES, reliabilities of LES were moderate to almost perfect for both homogeneity and diagnosis, only fair to moderate for OMERACTss, but increased in binary OMERACTss.
Videoconferencing training sessions in an international reliability exercise could be an excellent tool to train experienced and less-experienced sonographers. SGUS homogeneity items is useful to distinguish normal from abnormal salivary glands parenchyma independently of diagnosis. Structural damage evaluations by OMERACT scoring system is a new comprehensive score to diagnose patients with SD and could be easily used by sonographers in a binary method.
大唾液腺超声检查(SGUS)已证明其作为诊断原发性干燥综合征(SD)的一种结局指标具有良好的测量特性。目的是通过网络培训评估不同经验水平的超声检查医师之间SGUS的可靠性。
来自专家中心的超声检查医师参与了可靠性评估。在评估之前,通过视频会议进行培训。评估了两位经验最丰富的超声检查医师(MES)的可靠性,然后与其他超声检查医师进行比较。通过计算Cohen's κ系数评估SGUS项目的阅片者内和阅片者间可靠性。
所有14名超声检查医师在4个月的时间间隔内对所有病例组均进行了两次阅片。MES的阅片者内可靠性在同质性方面几乎完美,在风湿病结局测量(OMERACT)评分系统(OMERACTss)方面为实质性。在经验较少的超声检查医师(LES)中,同质性可靠性为中等至几乎完美,OMERACTss为一般至中等,二元OMERACTss为一般至几乎完美。MES之间的阅片者间可靠性在同质性方面几乎完美,诊断方面为实质性,OMERACTss为中等,二元OMERACTss为实质性。与MES相比,LES在同质性和诊断方面的可靠性均为中等至几乎完美,OMERACTss仅为一般至中等,但在二元OMERACTss中有所提高。
在国际可靠性评估中进行视频会议培训课程可能是培训经验丰富和经验较少的超声检查医师的极佳工具。SGUS同质性项目有助于独立于诊断区分正常和异常唾液腺实质。通过OMERACT评分系统进行的结构损伤评估是一种用于诊断SD患者的新综合评分,超声检查医师可以很容易地以二元方法使用。