热敏灸联合补肾活血方治疗肾虚血瘀型勃起功能障碍的随机对照研究。

Heat-sensitive moxibustion combined with powder for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial.

机构信息

Department of Reproductive Medicine, Henan Provincial Hospital of TCM, Second Affiliated Hospital of Henan University of CM, Zhengzhou 450002, China.

出版信息

Zhongguo Zhen Jiu. 2024 Feb 12;44(2):144-148. doi: 10.13703/j.0255-2930.20230409-0004.

DOI:10.13703/j.0255-2930.20230409-0004

PMID:38373758

Abstract

OBJECTIVES

To observe the clinical efficacy of heat-sensitive moxibustion combined with powder in treating erectile dysfunction with kidney deficiency and blood stasis.

METHODS

A total of 80 patients with erectile dysfunction of kidney deficiency and blood stasis were randomly divided into a comprehensive group (40 cases, 1 case dropped out) and a Chinese herb group (40 cases, 2 cases dropped out). In the Chinese herb group, powder was applied orally, one dose per day. On the basis of the Chinese herb group, heat-sensitive moxibustion was applied after detecting the heat-sensitive points in the areas of Guanyuan (CV 4), Zhongji (CV 3), Qihai (CV 6) and bilateral Xuehai (SP 10), Sanyinjiao (SP 6) in the comprehensive group, once a day, 5 times a week. Both groups were treated for 4 weeks. The international index of erectile function-5 (IIEF-5) score, erectile hardness score (EHS), nocturnal penile tumescence and rigidity (NPTR) indexes (nocturnal penile erection frequency, total duration of penile erection, duration of penile head hardness ≥60%, duration of penile root hardness ≥60%, percentage change in penile head circumference, percentage change in penile root circumference), TCM syndrome score, and penile vascular function indexes (peak systolic velocity [PSV], end diastolic velocity [EDV], and resistance index [RI] of penile cavernosal artery) were compared in the patients of the two groups before and after treatment, and the clinical efficacy was evaluated.

RESULTS

After treatment, the IIEF-5 scores, EHS, PSV, RI, and NPTR indexes were increased compared with those before treatment (<0.01), while the TCM syndrome scores and EDV were decreased compared with those before treatment (<0.01) in the two groups.The IIEF-5 score, EHS, PSV, RI, and NPTR indexes in the comprehensive group were ascended compared with those in the Chinese herb group (<0.01), while the TCM syndrome score and EDV in the comprehensive group were lower than those in the traditional Chinese herb group (0.01). The total effective rate of the comprehensive group was 94.9% (37/39), which was higher than 78.9% (30/38, <0.05) of the Chinese herb group.

CONCLUSIONS

The combination of heat-sensitive moxibustion and powder can effectively treat erectile dysfunction of kidney deficiency and blood stasis, improve patients' erectile function, enhance their erection hardness, and improve their penile vascular function and clinical symptoms.

摘要

目的

观察热敏灸联合散治疗肾虚血瘀型勃起功能障碍的临床疗效。

方法

将 80 例肾虚血瘀型勃起功能障碍患者随机分为综合组（40 例，脱落 1 例）和中药组（40 例，脱落 2 例）。中药组口服散，每日 1 剂。在中药组的基础上，综合组在检测到关元（CV4）、中极（CV3）、气海（CV6）和双侧血海（SP10）、三阴交（SP6）等区域的热敏点后，每天进行热敏灸治疗，每周 5 次。两组均治疗 4 周。比较两组患者治疗前后国际勃起功能指数-5（IIEF-5）评分、勃起硬度评分（EHS）、夜间阴茎勃起和硬度（NPTR）指标（夜间阴茎勃起频率、阴茎勃起总持续时间、阴茎头部硬度≥60%持续时间、阴茎根部硬度≥60%持续时间、阴茎头部周长变化百分比、阴茎根部周长变化百分比）、中医证候评分和阴茎血管功能指标（阴茎海绵体动脉收缩期峰值流速[PSV]、舒张末期流速[EDV]和阻力指数[RI]），并评价临床疗效。

结果

治疗后，两组 IIEF-5 评分、EHS、PSV、RI 和 NPTR 指标均较治疗前升高（<0.01），中医证候评分和 EDV 均较治疗前降低（<0.01）。综合组 IIEF-5 评分、EHS、PSV、RI 和 NPTR 指标均高于中药组（<0.01），中医证候评分和 EDV 均低于中药组（<0.01）。综合组总有效率为 94.9%（37/39），高于中药组的 78.9%（30/38，<0.05）。