Blazer V S, Gratzek J B
J Comp Pathol. 1985 Apr;95(2):273-80. doi: 10.1016/0021-9975(85)90013-1.
The pathology observed in a metacercarial (species not yet identified) infection of pond-raised, aquarium fish is described. In natural infections, there was extensive proliferation of cartilage resulting in loss of respiratory epithelium and occasionally in fusion of primary lamellae. Grossly, the most consistent sign of infection was flared opercula with protruding gills. Although haemorrhage was produced in early infections as the cercariae migrated, it was not macroscopically evident. A few heavily infected fish did have grossly observable signs of haemorrhage but this was not a consistent finding. Cercariae were collected from snails (Pleurocera sp.) and fish were experimentally infected to study the response. Over a 6-day-period, a progression from fibroblast to chondroblast occurred, indicating that piscine fibroblasts are able to differentiate into chondroblasts. This differentiation may be dependent on environmental conditions or may be stimulated by the parasite itself.
本文描述了在池塘养殖的水族箱鱼类中观察到的一种尾蚴（尚未鉴定出物种）感染的病理学情况。在自然感染中，软骨出现广泛增殖，导致呼吸上皮丧失，偶尔还会出现初级鳃小片融合。大体上，感染最一致的体征是鳃盖张开且鳃突出。虽然在尾蚴移行的早期感染阶段会产生出血，但肉眼观察并不明显。少数重度感染的鱼确实有肉眼可见的出血迹象，但这并非一个一致的发现。从蜗牛（Pleurocera属）中收集尾蚴，并对鱼进行实验性感染以研究其反应。在6天的时间段内，发生了从成纤维细胞到成软骨细胞的转变，这表明鱼类成纤维细胞能够分化为成软骨细胞。这种分化可能取决于环境条件，也可能受到寄生虫本身的刺激。
