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儿童偏头痛相关性眩晕的仪器评估与药物治疗

Instrumental Assessment and Pharmacological Treatment of Migraine-Related Vertigo in Pediatric Age.

作者信息

Viola Pasquale, Scarpa Alfonso, Chiarella Giuseppe, Pisani Davide, Astorina Alessia, Ricciardiello Filippo, De Luca Pietro, Re Massimo, Gioacchini Federico Maria

机构信息

Unit of Audiology, Regional Centre of Cochlear Implants and ENT Diseases, Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.

Department of Medicine and Surgery, University of Salerno, 84084 Salerno, Italy.

出版信息

Audiol Res. 2024 Jan 29;14(1):129-138. doi: 10.3390/audiolres14010011.

Abstract

BACKGROUND

The most frequent form of vertigo in pediatric age is represented by vertigo linked to migraine, with a prevalence of 32.7%. This group of pathologies has received a redefinition of the diagnostic criteria to adapt them to the pediatric age with a new classification of the clinical pictures. We have several kinds of problems with these conditions that often have a significant impact on patients' and parents' quality of life: the diagnostic approach involves different tools for the different age groups contained in the pediatric range; the treatment of this type of vertigo is not consolidated due to the limited availability of trials carried out on pediatric patients. Focusing on this topic, the aim of this review was to provide an update on the more recent clinical advances in the diagnosis and treatment of Vestibular Migraine (VM) in children.

METHODS

We searched the PubMed, Embase, and Cochrane library databases for articles published in English from January 2015 to April 2023. The secondary search included articles from reference lists, identified by the primary search. Records were first screened by title/abstract, and then full-text articles were retrieved for eligibility evaluation. The searches combined a range of key terms ("Pediatric" AND "Childhood" AND "dizziness" OR "vertigo" AND "vestibular").

RESULTS

Migraine-related vertigo, in its most recent definitions and classifications, is the most frequent group of balance pathologies in pediatric age. The results from the various experiences present in the literature suggest a clinical approach to be integrated with the use of instrumental tests selected according to the age of the patient and the reliability of the results.

CONCLUSION

Knowing the timeline of the applicability of vestibular tests and the information that can be obtained from them is fundamental for diagnostic accuracy. Therapy is strongly conditioned by the limited availability of pediatric trials and by the wide range it includes, from very young children to adolescents.

摘要

背景

儿童期最常见的眩晕形式是与偏头痛相关的眩晕,患病率为32.7%。这组疾病的诊断标准已重新定义,以使其适应儿童期,并对临床表现进行了新的分类。这些病症给我们带来了多种问题,常常对患者及其父母的生活质量产生重大影响:诊断方法因儿童年龄段不同而涉及不同工具;由于针对儿科患者进行的试验有限,这类眩晕的治疗方法尚未得到充分确立。围绕这一主题,本综述的目的是提供有关儿童前庭性偏头痛(VM)诊断和治疗方面最新临床进展的最新信息。

方法

我们在PubMed、Embase和Cochrane图书馆数据库中检索了2015年1月至2023年4月以英文发表的文章。二次检索包括通过一次检索确定的参考文献列表中的文章。记录首先通过标题/摘要进行筛选,然后检索全文文章进行资格评估。检索结合了一系列关键词(“儿科”、“儿童期”、“头晕”或“眩晕”、“前庭”)。

结果

在其最新定义和分类中,与偏头痛相关的眩晕是儿童期最常见的平衡障碍组。文献中各种经验的结果表明,临床方法应结合根据患者年龄和结果可靠性选择的仪器检查来综合应用。

结论

了解前庭测试的适用时间线以及可从中获得的信息对于诊断准确性至关重要。治疗受到儿科试验有限可用性以及所涵盖范围广泛(从幼儿到青少年)的强烈制约。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da9d/10886403/8e78cdc338f0/audiolres-14-00011-g001.jpg

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