Vicenti Caterina, Otero Pablo E, Briganti Angela, Rondelli Vincenzo, Stabile Marzia, Piemontese Claudia, Crovace Antonio, Lacitignola Luca, Staffieri Francesco
Section of Veterinary Clinics and Animal Production, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari, 70010 Valenzano, Italy.
Department of Anesthesiology and Pain Management, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires C1427CWN, Argentina.
Vet Sci. 2024 Feb 6;11(2):75. doi: 10.3390/vetsci11020075.
This study aimed to evaluate the benefits of applying 5 cmHO of CPAP using a pediatric helmet during the recovery phase from general anesthesia in brachycephalic dogs. Brachycephalic dogs undergoing various surgical procedures were included in this study, and a total of 64 subjects were randomly assigned to receive either standard oxygen supplementation (NO-CPAP group) or oxygen supplementation combined with CPAP (CPAP group). This study evaluated arterial blood pH, blood gas partial pressures of O and CO, arterial blood O saturation, and related parameters during recovery. The dogs were monitored, and helmet tolerance was assessed using predefined criteria. Of the initially assessed 69 dogs, 64 were enrolled: 32 in the CPAP group and 32 in the NO-CPAP group. Fifteen dogs in the NO-CPAP group were excluded based on predetermined criteria. The CPAP group showed significant improvements in PaO, PaO/FiO, P(A-a)O, F-Shunt, and respiratory rate compared with the NO-CPAP group ( < 0.001). The incidence of reintubation and helmet intolerance was higher in the NO-CPAP group (18% and 15.6%, respectively) than in the CPAP group (0%). This study highlights the potential benefits of incorporating CPAP, delivered through a pediatric helmet, in the perioperative management of brachycephalic dogs.
本研究旨在评估在短头犬全身麻醉恢复期使用儿童头盔给予5 cmHO持续气道正压通气(CPAP)的益处。本研究纳入了接受各种外科手术的短头犬,共64只受试动物被随机分配接受标准氧疗(非CPAP组)或氧疗联合CPAP(CPAP组)。本研究评估了恢复期的动脉血pH值、氧和二氧化碳的血气分压、动脉血氧饱和度及相关参数。对犬进行监测,并使用预先定义的标准评估头盔耐受性。在最初评估的69只犬中,64只被纳入研究:CPAP组32只,非CPAP组32只。根据预定标准,非CPAP组有15只犬被排除。与非CPAP组相比,CPAP组的动脉血氧分压(PaO)、氧合指数(PaO/FiO)、肺泡-动脉血氧分压差[P(A-a)O]、分流分数(F-Shunt)和呼吸频率均有显著改善(P<0.001)。非CPAP组的再次插管发生率和头盔不耐受发生率(分别为18%和15.6%)高于CPAP组(0%)。本研究强调了在短头犬围手术期管理中采用通过儿童头盔给予CPAP的潜在益处。