Department of Medical Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Department of Econometrics and Operations Research, Tilburg University, Tilburg, The Netherlands.
Cancer. 2024 Jul 1;130(13):2372-2383. doi: 10.1002/cncr.35260. Epub 2024 Feb 23.
The aim of this population-based registry study was to examine the impact of cancer on employment outcomes in adolescent and young adult (AYA) survivors and their partners and associated sociodemographic and clinical characteristics.
A total of 2456 AYA cancer patients, diagnosed in 2013 and aged 18 through 39 years old, were selected from the Netherlands Cancer Registry and linked to employment data from Statistics Netherlands, from which 1252 partners of AYAs could be identified. For both patients and their partners, a control group with same age, migration background, and sex was selected. The impact (i.e., causal effect) was estimated by implementing a doubly robust difference-in-differences method, from 3 years before to 5 years after cancer diagnosis.
Patients suffered a reduced employment probability (3.8 percentage points) and number of hours worked when employed (3.8%). This effect was larger for females, and individuals with a migration background, high tumor stage, or diagnosed with a central nervous system tumor/hematologic malignancy. In regard to employment, no significant effect could be found for the patients' partners, although a 5.5 percentage-point increase in employment probability was found in partners who were either unemployed or worked fewer than 400 hours.
A cancer diagnosis significantly affects employment outcomes of AYA patients with cancer. Patients at risk should have access to services such as job counseling to help them return into society in the best possible way. No objective impact on partners' employment outcomes was found; however, subjective well-being was not taken into account.
This study estimated the causal effect of a cancer diagnosis on employment outcomes. Adolescent and young adult cancer survivors face a reduction in both employment probability and the number of hours worked when employed. Partners that were unemployed or worked the least number of hours a year before diagnosis had a 5.5 percentage-point increased employment probability, but for other partners effects are small.
本基于人群的登记研究旨在探讨癌症对青少年和年轻成人(AYA)幸存者及其伴侣的就业结果的影响,并分析相关的社会人口学和临床特征。
从荷兰癌症登记处选取了 2456 名于 2013 年诊断为年龄在 18 至 39 岁的 AYA 癌症患者,并与荷兰统计局的就业数据相链接,在此基础上确定了 1252 名 AYA 的伴侣。为患者及其伴侣均选择了年龄、移民背景和性别相同的对照组。通过实施双重稳健差分差异法,从癌症诊断前 3 年到后 5 年,评估了影响(即因果效应)。
患者的就业概率(3.8 个百分点)和就业时的工作小时数(3.8%)均降低。对于女性、有移民背景、肿瘤分期较高或患有中枢神经系统肿瘤/血液恶性肿瘤的个体,这种影响更大。关于就业,患者的伴侣没有表现出显著的影响,尽管那些失业或工作少于 400 小时的伴侣的就业概率增加了 5.5 个百分点。
癌症诊断显著影响 AYA 癌症患者的就业结果。有风险的患者应该能够获得职业咨询等服务,以帮助他们以最佳方式重返社会。没有发现对伴侣就业结果的客观影响;但是,没有考虑主观幸福感。