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微创治疗的证据——关于椎间盘移位手术治疗的系统评价。

Evidence for minimally invasive treatment-A systematic review on surgical management of disc displacement.

机构信息

Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.

Medical Unit of Plastic Surgery and Oral and Maxillofacial Surgery, Karolinska University Hospital, Stockholm, Sweden.

出版信息

J Oral Rehabil. 2024 Jun;51(6):1061-1080. doi: 10.1111/joor.13661. Epub 2024 Feb 23.

Abstract

BACKGROUND

Surgical treatment of temporomandibular joint (TMJ) disc displacement (DD) has been established in different forms since over a century. Ther is a consensus to perform minimal invasive interventions as first-line surgical treatment since there are no evidence on best surgical practice yet.

OBJECTIVE

The aim was to perform a complex systematic review (SR) on the topic-is there evidence for surgical treatment of TMJ DD?

METHODS

The PICO was defined as DD patients (population), treated with different surgical interventions including arthrocentesis (intervention), compared with other or no treatment (control) regarding the outcome variables mandibular function, mouth opening capacity, TMJ pain, etcetera (outcome). For identification of prospective controlled trials and SRs, a search strategy was developed for application in three databases.

RESULTS

The search yielded 4931 studies of which 56 fulfilled the stipulated PICO. Studies with low or moderate risk of bias were possible to include in meta-analyses. There were evidence suggesting arthrocentesis being more effective compared to conservative management (maximum interincisal opening (MIO): p < .0001, I = 22%; TMJ pain: p = .0003, I = 84%) and arthrocentesis being slightly more effective than arthrocentesis with an adjunctive hyaluronic acid injection (MIO: p = .04, I = 0%; TMJ pain: p = .28, I = 0%). Other treatment comparisons showed nonsignificant differences. The performed meta-analyses only included 2-4 studies each, which might indicate a low grade of evidence.

CONCLUSION

Although arthrocentesis performed better than conservative management the findings should be interpreted cautiously, and non-invasive management considered as primary measure. Still, several knowledge gaps concerning surgical methods of choice remains.

摘要

背景

自一个多世纪以来,针对颞下颌关节(TMJ)盘移位(DD)的手术治疗已经有了多种形式。由于目前尚无最佳手术实践的证据,因此共识是将微创干预作为一线手术治疗。

目的

旨在就 TMJ DD 的手术治疗是否有证据这一主题进行综合系统评价(SR)。

方法

PICO 定义为 DD 患者(人群),采用包括关节穿刺术(干预)在内的不同手术干预措施进行治疗,与其他治疗或不治疗(对照)相比,观察下颌功能、张口能力、TMJ 疼痛等结局变量。为了确定前瞻性对照试验和 SR,制定了一个搜索策略,应用于三个数据库。

结果

搜索结果为 4931 项研究,其中 56 项符合规定的 PICO。存在低或中度偏倚风险的研究可纳入荟萃分析。有证据表明关节穿刺术比保守治疗更有效(最大开口度(MIO):p < 0.0001,I = 22%;TMJ 疼痛:p = 0.0003,I = 84%),关节穿刺术联合透明质酸注射辅助治疗比关节穿刺术稍有效(MIO:p = 0.04,I = 0%;TMJ 疼痛:p = 0.28,I = 0%)。其他治疗比较显示无显著性差异。进行的荟萃分析每项仅包括 2-4 项研究,这可能表明证据等级较低。

结论

尽管关节穿刺术比保守治疗效果更好,但这些发现应谨慎解释,并将非侵入性治疗作为主要措施。然而,关于手术方法选择的几个知识空白仍然存在。

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