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从右胸动脉或主动脉到右冠状动脉系统的隐静脉。 2 组的长期倾向性匹配结果。

Saphenous vein to the right coronary system from the right thoracic artery or the aorta. Long-term propensity-matched results of 2 groups.

机构信息

1st Department of Cardiac Surgery A, Henry Dunant Hospital, Athens, Greece.

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA.

出版信息

Eur J Cardiothorac Surg. 2024 Mar 1;65(3). doi: 10.1093/ejcts/ezae060.

Abstract

OBJECTIVES

Since 2000, we anastomosed the saphenous vein graft to the right coronary artery system using the stump of the right internal thoracic artery as inflow. The long-term results of patients where the right coronary artery was grafted with the right internal thoracic artery or the ascending aorta as saphenous vein inflow has not been reported.

METHODS

From 2000 to 2018, 699 consecutive patients had right internal thoracic artery elongated with saphenous vein (I-graft group, n = 358, 51.2%) or saphenous vein from the aorta (Ao-graft group, n = 341, 48.8%) on right coronary artery system. Inclusion criteria were age ≤75 years, bilateral internal thoracic arteries as a Y graft on the left system (three-vessel disease, n = 603, 86.3%) or as a left internal thoracic artery on left anterior descending and right internal thoracic artery elongated with saphenous vein on the right coronary artery system (two-vessel disease, n = 96, 13.7%), only 1 saphenous vein per patient. Propensity-matching identified 272 patients per group. One-hundred and twenty-two patients underwent coronary computed tomographic angiography to asses grafts patency after a median follow-up of 88 (65-93) months.

RESULTS

In the paired samples, there was no difference in the early outcome. Ten-year survival and freedom from death, non-fatal acute myocardial infarction and repeat revascularization were higher in I-graft group: 90.6 [standard error (SE): 2.0] vs 78.2 (SE: 5.3), P = 0.0266, and 85.2 (SE: 2.4) vs 69.9 (SE: 5.3), P = 0.0179. Saphenous vein graft, at a long-time follow-up, showed a higher patency rate (81.6% (SE: 7.0) vs 50.7% (SE: 7.9), P < 0.0001) and a smaller internal lumen diameter (2.7, standard deviation: 0.4 vs 3.4, standard deviation: 0.6 mm, P < 0.0001) when right internal thoracic artery was the inflow.

CONCLUSIONS

Grafting the right coronary artery with saphenous vein may entail higher patency rate and better outcome when the inflow is the right internal thoracic artery than when is the ascending aorta. Prospective randomized data are needed to test this hypothesis.

摘要

目的

自 2000 年以来,我们使用右内乳动脉残端作为流入道,将大隐静脉吻合到右冠状动脉系统。将右冠状动脉用右内乳动脉或升主动脉作为大隐静脉流入道进行搭桥的患者的长期结果尚未报道。

方法

2000 年至 2018 年,699 例连续患者在右冠状动脉系统中使用大隐静脉延长右内乳动脉(I-移植物组,n=358,51.2%)或主动脉大隐静脉(Ao-移植物组,n=341,48.8%)。纳入标准为年龄≤75 岁,双侧内乳动脉作为左系统的 Y 移植物(三血管病变,n=603,86.3%)或左前降支和右内乳动脉作为左前降支,右冠状动脉系统中的大隐静脉延长(两血管病变,n=96,13.7%),每位患者仅使用 1 根大隐静脉。倾向匹配每组确定 272 例患者。122 例患者接受冠状动脉计算机断层血管造影术,以评估中位数随访 88(65-93)个月后的移植物通畅情况。

结果

在配对样本中,早期结果无差异。I 移植物组 10 年生存率和无死亡、非致死性急性心肌梗死和再次血运重建率更高:90.6[标准误差(SE):2.0] vs 78.2(SE:5.3),P=0.0266,85.2(SE:2.4)vs 69.9(SE:5.3),P=0.0179。大隐静脉移植物在长期随访中显示出更高的通畅率(81.6%(SE:7.0)vs 50.7%(SE:7.9),P<0.0001)和更小的内部管腔直径(2.7,标准差:0.4 vs 3.4,标准差:0.6mm,P<0.0001),当右内乳动脉为流入道时。

结论

当流入道为右内乳动脉而不是升主动脉时,用大隐静脉为右冠状动脉搭桥可能会获得更高的通畅率和更好的结果。需要前瞻性随机数据来验证这一假设。

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