• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

感染性心内膜炎赘生物的栓塞可导致缺血性卒中后颅内出血并伴有出血性转化。

Embolization of infective endocarditis vegetation causes intracranial hemorrhage with hemorrhagic transformation after ischemic stroke.

作者信息

Aslani Averina O, Haryawan Zahran, Sabrawi Tania A, Wibowo Robin H, Dewi Aprilianasary U

机构信息

Sumedang Regional General Hospital, Sumedang, West Java, Indonesia.

Ciamis Regional General Hospital, Ciamis, West Java, Indonesia.

出版信息

Glob Cardiol Sci Pract. 2024 Jan 3;2024(1):e202402. doi: 10.21542/gcsp.2024.2.

DOI:10.21542/gcsp.2024.2
PMID:38404657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10886705/
Abstract

BACKGROUND

Infective endocarditis (IE) is a rare, but potentially fatal, infectious disease. One of the common complications of IE is the embolization of endocardial vegetation with subsequent intracerebral artery obstruction that causes acute ischemic stroke. Herein, we present a case report of a patient presenting with a neurological manifestation that turned out to be a complication of IE.

CASE ILLUSTRATION

We present the case of a patient with a chief complaint of left-sided hemiplegia. Blood test results revealed signs of infection. Computed tomography (CT) of the head revealed extensive infarction in the right lobe and subarachnoid hemorrhage. Echocardiography revealed vegetation on the aortic valve, suggesting that IE was the source of embolization. The patient was treated with high-dose ampicillin and gentamicin, supportive stroke therapy, and physical rehabilitation.

CONCLUSION

IE can be considered one of the causes of acute ischemic or hemorrhagic stroke. Ruling out other common causes of stroke and noticing signs of infection and vascular phenomena helps define the diagnosis. Echocardiography helps identify valvular vegetation to support the diagnosis. Treatment consists of high-dose penicillin and supportive therapy for stroke.

摘要

背景

感染性心内膜炎(IE)是一种罕见但可能致命的传染病。IE的常见并发症之一是心内膜赘生物栓塞,随后导致脑动脉阻塞,引起急性缺血性中风。在此,我们报告一例以神经系统表现为特征的病例,结果发现是IE的并发症。

病例说明

我们报告一例以左侧偏瘫为主诉的患者。血液检查结果显示有感染迹象。头部计算机断层扫描(CT)显示右叶广泛梗死和蛛网膜下腔出血。超声心动图显示主动脉瓣上有赘生物,提示IE是栓塞的来源。患者接受了大剂量氨苄青霉素和庆大霉素治疗、支持性中风治疗以及物理康复治疗。

结论

IE可被视为急性缺血性或出血性中风的病因之一。排除其他常见的中风病因并注意感染迹象和血管现象有助于明确诊断。超声心动图有助于识别瓣膜赘生物以支持诊断。治疗包括大剂量青霉素和中风支持治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/b06c0bf18158/gcsp-2024-1-e202402-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/c7553a0fd501/gcsp-2024-1-e202402-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/abe9554f02a2/gcsp-2024-1-e202402-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/b06c0bf18158/gcsp-2024-1-e202402-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/c7553a0fd501/gcsp-2024-1-e202402-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/abe9554f02a2/gcsp-2024-1-e202402-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47f/10886705/b06c0bf18158/gcsp-2024-1-e202402-g003.jpg

相似文献

1
Embolization of infective endocarditis vegetation causes intracranial hemorrhage with hemorrhagic transformation after ischemic stroke.感染性心内膜炎赘生物的栓塞可导致缺血性卒中后颅内出血并伴有出血性转化。
Glob Cardiol Sci Pract. 2024 Jan 3;2024(1):e202402. doi: 10.21542/gcsp.2024.2.
2
Infective Endocarditis Presenting with Intracranial Bleeding.伴有颅内出血的感染性心内膜炎
J Emerg Med. 2016 Jul;51(1):50-4. doi: 10.1016/j.jemermed.2016.04.003. Epub 2016 May 25.
3
[Clinical study of stroke in young adults with infective endocarditis].[感染性心内膜炎青年卒中患者的临床研究]
Zhonghua Nei Ke Za Zhi. 2015 Sep;54(9):753-7.
4
A Cryptogenic Stroke Associated With Infective Endocarditis and Antiphospholipid Antibody Syndrome: Case Report and Literature Review.一例与感染性心内膜炎和抗磷脂抗体综合征相关的隐源性卒中:病例报告及文献综述
Front Neurol. 2022 Jul 25;13:872279. doi: 10.3389/fneur.2022.872279. eCollection 2022.
5
Transcatheter aortic valve replacement associated infective endocarditis case series: broadening the criteria for diagnosis is the need of the hour.经导管主动脉瓣置换术后感染性心内膜炎病例系列:拓宽诊断标准迫在眉睫。
BMC Cardiovasc Disord. 2021 Nov 20;21(1):559. doi: 10.1186/s12872-021-02364-0.
6
Clinical characteristics and thrombolytic outcomes of infective endocarditis-associated stroke.感染性心内膜炎相关卒中的临床特征及溶栓结局
Neurohospitalist. 2012 Jul;2(3):87-91. doi: 10.1177/1941874412446199.
7
causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report.导致感染性心内膜炎伴脑梗死和蛛网膜下腔出血:一例报告
Front Med (Lausanne). 2023 May 3;10:1117474. doi: 10.3389/fmed.2023.1117474. eCollection 2023.
8
Incidence, Clinical Characteristics, and Impact of Absent Echocardiographic Signs in Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation.经导管主动脉瓣植入术后感染性心内膜炎患者超声心动图征象缺失的发生率、临床特征及影响
Clin Infect Dis. 2023 Mar 21;76(6):1003-1012. doi: 10.1093/cid/ciac872.
9
Management of Large Vessel Occlusion Stroke Related to Infective Endocarditis: Is Mechanical Thrombectomy a Safe Option?感染性心内膜炎相关大血管闭塞性卒中的管理:机械取栓是一种安全的选择吗?
J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105248. doi: 10.1016/j.jstrokecerebrovasdis.2020.105248. Epub 2020 Aug 20.
10
Residual vegetation after treatment for left-sided infective endocarditis and subsequent risk of stroke and recurrence of endocarditis.左侧感染性心内膜炎治疗后的残余赘生物与随后的卒中风险和心内膜炎复发。
Int J Cardiol. 2019 Oct 15;293:67-72. doi: 10.1016/j.ijcard.2019.06.059. Epub 2019 Jun 22.

本文引用的文献

1
Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management.缺血性卒中后的出血性转化:机制与管理
Front Neurol. 2021 Nov 30;12:703258. doi: 10.3389/fneur.2021.703258. eCollection 2021.
2
Long-term Outcome of Neurological Complications after Infective Endocarditis.感染性心内膜炎后神经系统并发症的长期预后。
Sci Rep. 2020 Mar 4;10(1):3994. doi: 10.1038/s41598-020-60995-3.
3
Endocarditis and stroke.心内膜炎与中风。
Maedica (Bucur). 2014 Dec;9(4):375-81.
4
Infective endocarditis involving apparently structurally normal valves in patients without previously recognized predisposing heart disease.感染性心内膜炎累及既往无公认易患心脏病的患者中看似结构正常的瓣膜。
J Am Coll Cardiol. 2015 Jan 27;65(3):307-9. doi: 10.1016/j.jacc.2014.10.046.
5
Global and regional burden of infective endocarditis, 1990-2010: a systematic review of the literature.1990 - 2010年感染性心内膜炎的全球和地区负担:文献系统评价
Glob Heart. 2014 Mar;9(1):131-43. doi: 10.1016/j.gheart.2014.01.002.
6
Intracranial hemorrhage in infective endocarditis: A case report.感染性心内膜炎并发颅内出血:病例报告。
J Thorac Dis. 2011 Jun;3(2):134-7. doi: 10.3978/j.issn.2072-1439.2010.11.13.
7
Anticoagulation in patients with stroke with infective endocarditis: the sword of Damocles.感染性心内膜炎所致卒中患者的抗凝治疗:达摩克利斯之剑。
Stroke. 2011 Jun;42(6):1799-800. doi: 10.1161/STROKEAHA.111.622423. Epub 2011 May 5.
8
Intracranial infectious aneurysm: presentation, management and outcome.颅内感染性动脉瘤:临床表现、治疗及预后
J Neurol Sci. 2007 May 15;256(1-2):3-9. doi: 10.1016/j.jns.2007.01.044. Epub 2007 Mar 23.
9
Infective endocarditis in the intensive care unit: clinical spectrum and prognostic factors in 228 consecutive patients.重症监护病房中的感染性心内膜炎:228例连续患者的临床谱及预后因素
Intensive Care Med. 2004 Nov;30(11):2046-52. doi: 10.1007/s00134-004-2436-9. Epub 2004 Sep 15.
10
Age-related prevalence of cardiac valvular abnormalities warranting infectious endocarditis prophylaxis.需要进行感染性心内膜炎预防的心脏瓣膜异常的年龄相关患病率。
Am J Cardiol. 2004 Aug 1;94(3):386-9. doi: 10.1016/j.amjcard.2004.04.045.