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初次半月板修复或初次半月板切除术后5年转换为膝关节置换术的累积发病率及相关危险因素。

The cumulative incidence and risk factors associated with 5-year conversion to knee arthroplasty following primary meniscus repair or primary meniscectomy.

作者信息

Bracey Lauren, Parsons Dylan, Zhao Amy Y, Agarwal Amil R, Mikula Jacob D, Fraychineaud Thomas, Thakkar Savyasachi C, Doerre Teresa, Best Matthew J

机构信息

Department of Orthopaedic Surgery, George Washington Hospital, Washington DC, USA.

Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.

出版信息

J Orthop. 2024 Feb 10;52:17-20. doi: 10.1016/j.jor.2024.02.018. eCollection 2024 Jun.

Abstract

BACKGROUND

This study aimed to observe the 5-year knee arthroplasty conversion incidence rate and associated risk factors in patients who underwent meniscus procedures.

METHODS

Using a national database, we analyzed patients who had undergone primary meniscus repair or meniscectomy without prior knee surgeries. The cumulative knee arthroplasty conversion incidence was determined via Kaplan Meier analysis. Risk factors for conversion within 5 years were assessed using a Cox proportional hazard ratio model, with results as hazard ratios (HR).

RESULTS

8125 patients had meniscus repair, while 240,209 had meniscectomy. 5-year conversion rates: repair 1.7%, meniscectomy 8.4%. Arthroplasty likelihood decreased as age decreased for repair (70+ [HR: 162.20]; 60-69 [HR: 81.64]; 50-59 [HR: 49.85]; 40-49 [HR: 17.79]; p < 0.001 all). Additional risk factors included male sex (HR: 0.35; p < 0.001) and higher Charlson Comorbidity Index (CCI) (CCI1 [HR: 1.28; p = 0.012]). For meniscectomy, arthroplasty likelihood also decreased with age (70+ [HR: 99.41]; 60-69 [HR: 84.57]; 50-59 [HR: 66.60]; 40-49 [HR: 36.15]; 30-39 [HR: 10.18]; p < 0.001 all). Additional risk factors included male sex (HR: 0.68; p < 0.001), obesity (HR: 1.18; p < 0.001), smoking (HR: 0.1.12; p = 0.010), and higher CCI (CCI1 [HR: 1.25]; CCI2 [HR 1.39]; CCI3+ [HR 1.46]; p < 0.001 all).

CONCLUSION

This study revealed the national 5-year conversion incidence following primary meniscus repair (1.7%) and meniscectomy (8.4%). It also enhanced understanding of age, sex, obesity, smoking, comorbidities (CCI), and knee arthroplasty likelihood after meniscus procedures.

摘要

背景

本研究旨在观察接受半月板手术患者的5年膝关节置换转换发生率及相关危险因素。

方法

利用国家数据库,我们分析了未接受过膝关节手术且接受初次半月板修复或半月板切除术的患者。通过Kaplan Meier分析确定累积膝关节置换转换发生率。使用Cox比例风险模型评估5年内转换的危险因素,结果以风险比(HR)表示。

结果

8125例患者接受半月板修复,240209例接受半月板切除术。5年转换率:修复组为1.7%,半月板切除组为8.4%。对于修复组,随着年龄降低,膝关节置换的可能性降低(70岁及以上[HR:162.20];60 - 69岁[HR:81.64];50 - 59岁[HR:49.85];40 - 49岁[HR:17.79];所有p < 0.001)。其他危险因素包括男性(HR:0.35;p < 0.001)和更高的Charlson合并症指数(CCI)(CCI1 [HR:1.28;p = 0.012])。对于半月板切除组,膝关节置换的可能性也随年龄降低(70岁及以上[HR:99.41];60 - 69岁[HR:84.57];50 - 59岁[HR:66.60];40 - 49岁[HR:36.15];30 - 39岁[HR:10.18];所有p < 0.001)。其他危险因素包括男性(HR:0.68;p < 0.001)、肥胖(HR:1.18;p < 0.001)、吸烟(HR:1.12;p = 0.010)和更高的CCI(CCI1 [HR:1.25];CCI2 [HR 1.39];CCI3及以上[HR 1.46];所有p < 0.001)。

结论

本研究揭示了初次半月板修复(1.7%)和半月板切除术后(8.4%)的全国5年转换发生率。它还增进了对年龄、性别、肥胖、吸烟、合并症(CCI)以及半月板手术后膝关节置换可能性的理解。

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