Division of Arrhythmology, Shizuoka Saiseikai General Hospital, Shizuoka, Japan.
Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Japan.
J Cardiovasc Electrophysiol. 2024 Apr;35(4):802-810. doi: 10.1111/jce.16226. Epub 2024 Feb 26.
The Mt. FUJI multicenter trial demonstrated that a delivery catheter system had a higher rate of successful right ventricular (RV) lead deployment on the RV septum (RVS) than a conventional stylet system. In this subanalysis of the Mt. FUJI trial, we assessed the differences in electrocardiogram (ECG) parameters during RV pacing between a delivery catheter system and a stylet system and their associations with the lead tip positions.
Among 70 patients enrolled in the Mt FUJI trial, ECG parameters, RV lead tip positions, and lead depth inside the septum assessed by computed tomography were compared between the catheter group (n = 36) and stylet group (n = 34).
The paced QRS duration (QRS-d), corrected paced QT (QTc), and JT interval (JTc) were significantly shorter in the catheter group than in the stylet group (QRS-d: 130 ± 19 vs. 142 ± 15 ms, p = .004; QTc: 476 ± 25 vs. 514 ± 20 ms, p < .001; JTc: 347 ± 24 vs. 372 ± 17 ms, p < .001). This superiority of the catheter group was maintained in a subgroup analysis of patients with an RV lead tip position at the septum. The lead depth inside the septum was greater in the catheter group than in the stylet group, and there was a significant negative correlation between the paced QRS-d and the lead depth.
Using a delivery catheter system carries more physiological depolarization and repolarization during RVS pacing and deeper screw penetration in the septum in comparison to conventional stylet system. The lead depth could have a more impact on the ECG parameters rather than the type of pacing lead.
富士山多中心试验表明,与传统的导丝系统相比,一种输送导管系统在右心室(RV)间隔(RVS)上成功部署 RV 导联的比例更高。在富士山试验的这项亚分析中,我们评估了输送导管系统与导丝系统在 RV 起搏时心电图(ECG)参数的差异,及其与导联尖端位置的关系。
在富士山试验中,共纳入 70 例患者,我们比较了导管组(n=36)和导丝组(n=34)的心电图参数、RV 导联尖端位置和 CT 评估的间隔内导联深度。
导管组的起搏 QRS 时限(QRS-d)、校正起搏 QT(QTc)和 JT 间期(JTc)明显短于导丝组(QRS-d:130±19 比 142±15 ms,p=0.004;QTc:476±25 比 514±20 ms,p<0.001;JTc:347±24 比 372±17 ms,p<0.001)。在 RV 导联尖端位于间隔的患者亚组分析中,导管组的这种优势仍然存在。导管组的间隔内导联深度大于导丝组,起搏 QRS-d 与导联深度呈显著负相关。
与传统的导丝系统相比,使用输送导管系统在 RVS 起搏时可产生更生理性的去极化和复极化,且在间隔内的螺钉穿透更深。导联深度可能对 ECG 参数的影响更大,而不是起搏导联的类型。