Rehnberg O, Olbe L
Acta Chir Scand. 1985;151(6):565-9.
Risk factors for postoperative early dumping symptoms were studied prospectively in 289 consecutive peptic ulcer patients followed up for 5 years after antrectomy and gastroduodenostomy with or without vagotomy. Grade 2 or 3 dumping was present in 14% of the patients and was about four times as frequent in women as in men after antrectomy alone. The incidence of such dumping grades was twice as high after combined antrectomy and vagotomy as after antrectomy alone. Both differences were statistically significant. Milk intolerance, which often appeared as a symptom of dumping, was more common after combined antrectomy and vagotomy. Dumping seemed primarily to be related to the sex of the patient or to milk intolerance, whereas vagotomy additional to antrectomy seemed to enhance the risk of incurring dumping by causing milk intolerance. Grade 2 or 3 dumping was statistically associated with postoperative loss of weight. Pre operative apomorphine test was performed with the aim of detecting predisposition to postoperative dumping reaction. The authors conclude that apomorphine test preoperatively cannot predict postoperative dumping.
对289例连续性消化性溃疡患者进行了前瞻性研究，这些患者在接受胃窦切除术和胃十二指肠吻合术（伴或不伴迷走神经切断术）后随访了5年，以探讨术后早期倾倒综合征的危险因素。2级或3级倾倒综合征在14%的患者中出现，在单纯胃窦切除术后，女性患者出现该症状的频率约为男性患者的四倍。联合胃窦切除术和迷走神经切断术后，此类倾倒综合征的发生率是单纯胃窦切除术后的两倍。这两个差异均具有统计学意义。牛奶不耐受常表现为倾倒综合征的症状，在联合胃窦切除术和迷走神经切断术后更为常见。倾倒综合征似乎主要与患者性别或牛奶不耐受有关，而在胃窦切除术基础上附加迷走神经切断术似乎会因导致牛奶不耐受而增加发生倾倒综合征的风险。2级或3级倾倒综合征与术后体重减轻具有统计学相关性。术前进行阿扑吗啡试验，目的是检测术后倾倒反应的易感性。作者得出结论，术前阿扑吗啡试验无法预测术后倾倒综合征。
