单瓣术式与不使用浓缩生长因子治疗牙周骨上缺损的随机对照临床试验
Single-flap approach versus without concentrate growth factor in the treatment of periodontal supra-osseous defects: A randomized controlled clinical trial.
作者信息
El-Wakeel Naglaa, Mohamed Abd-Elaziz Lobna
机构信息
Oral Medicine and Periodontology Department, Faculty of Dentistry, Al-Azhar University (Girls Branch), Cairo, Egypt.
出版信息
Saudi Dent J. 2024 Feb;36(2):328-333. doi: 10.1016/j.sdentj.2023.11.015. Epub 2023 Nov 15.
OBJECTIVES
We aimed to compare treatment outcomes of periodontal supra-bony defects using single flap (SFA) plus concentrate growth factor versus SFA alone
METHODS
32 supra-bony periodontal defects were randomly assigned to test and control groups. Outcome variables were clinical attachment level (primary outcome). Probing pocket depths, gingival recessions, bone gain, post-surgical pain using visual analogue scale and wound healing index were recorded as secondary outcomes. Clinical and radiographic assessments were recorded at baseline and 6 months after treatment, whereas pain score and wound healing index were recorded within 10 days after surgery.
RESULTS
Test group showed a significant improvement in all tested parameters compared to control group (P-value ≤ 0.05). Better patient centered outcomes (wound healing and pain scores) were highly achieved in the test group compared to controls.
CONCLUSION
The tested combined approach offers better periodontal and patient centered treatment outcomes in management of periodontal supra-bony defects.
目的
我们旨在比较单瓣术（SFA）联合浓缩生长因子与单纯SFA治疗牙周骨上袋缺损的效果。
方法
将32例牙周骨上袋缺损随机分为试验组和对照组。主要观察指标为临床附着水平（主要结局）。次要结局包括探诊深度、牙龈退缩、骨增量、采用视觉模拟量表评估的术后疼痛以及伤口愈合指数。在基线和治疗后6个月进行临床和影像学评估，而疼痛评分和伤口愈合指数在术后10天内记录。
结果
与对照组相比，试验组在所有检测参数上均有显著改善（P值≤0.05）。与对照组相比，试验组在以患者为中心的结局（伤口愈合和疼痛评分）方面表现更佳。
结论
在牙周骨上袋缺损的治疗中，所测试的联合治疗方法能带来更好的牙周和以患者为中心的治疗效果。
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