Ponatinib-Induced Cardiomyocyte Toxicity: Dark Side of the Integrated Stress Response.
作者信息
Liang Felix G, Moslehi Javid, Kitsis Richard N
机构信息
Department of Cell Biology (F.G.L., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
Wilf Family Cardiovascular Research Institute (F.G.L., R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
出版信息
Circ Res. 2024 Mar;134(5):502-504. doi: 10.1161/CIRCRESAHA.124.324164. Epub 2024 Feb 29.
Abstract
摘要
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本文引用的文献
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2
Ponatinib Drives Cardiotoxicity by S100A8/A9-NLRP3-IL-1β Mediated Inflammation.泊那替尼通过 S100A8/A9-NLRP3-IL-1β 介导的炎症诱导心脏毒性。
Circ Res. 2023 Feb 3;132(3):267-289. doi: 10.1161/CIRCRESAHA.122.321504. Epub 2023 Jan 10.
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Targeting integrated stress response with ISRIB combined with imatinib treatment attenuates RAS/RAF/MAPK and STAT5 signaling and eradicates chronic myeloid leukemia cells.靶向整合应激反应的 ISRIB 联合伊马替尼治疗可抑制 RAS/RAF/MAPK 和 STAT5 信号通路并根除慢性髓性白血病细胞。
BMC Cancer. 2022 Dec 2;22(1):1254. doi: 10.1186/s12885-022-10289-w.
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Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.线粒体应激诱导对心肌病具有保护作用的HRI-eIF2α信号通路。
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