上消化道出血与下消化道出血患者血常规检查参数的差异分析。

Differential Analysis of Blood Routine Examination Parameters in Patients with Upper Gastrointestinal Bleeding and Lower Gastrointestinal Bleeding.

出版信息

Altern Ther Health Med. 2024 Nov;30(11):98-102.

Abstract

BACKGROUND

This study addresses the critical need for differentiating between upper and lower gastrointestinal bleeding by focusing on blood routine parameters to enhance diagnostic precision.

OBJECTIVE

This study aims to identify and compare specific blood routine parameters to determine their efficacy in distinguishing between upper and lower gastrointestinal bleeding for improved clinical decision-making.

METHODS

This retrospective study analyzed 119 patients with gastrointestinal bleeding (GIB) admitted to our hospital between January 2017 and June 2020. Among them, 86 were diagnosed with upper GIB (UGIB) and 33 with lower GIB (LGIB). After admission, peripheral blood samples were collected for a comprehensive blood routine examination, including white blood cell count (WBC), red blood cell count (RBC), hemoglobin (Hb), platelet count (PLT), blood urea nitrogen (BUN), creatinine (Cr), and BUN to Cr ratio (BUN/Cr ratio). Differences in blood routine parameters were compared between the UGIB and LGIB groups. Receiver Operating Characteristic (ROC) curve analysis was conducted to assess the efficacy of blood routine examinations in differentiating between UGIB and LGIB.

RESULTS

The study revealed no significant differences in WBC and Cr levels between LGIB and UGIB patients (P > .05). However, UGIB patients exhibited statistically lower levels of RBC, Hb, and PLT, along with higher BUN and BUN/Cr ratio levels compared to LGIB patients (P < .05). Pearson correlation coefficient analysis indicated an inverse correlation of BUN/Cr with RBC, Hb, and PLT in GIB patients and a positive association between BUN/Cr and BUN (P < .05). ROC analysis demonstrated that RBC, Hb, PLT, BUN, and BUN/Cr ratios were effective in distinguishing UGIB from LGIB (P < .05).

CONCLUSIONS

Blood routine parameters, including RBC, Hb, PLT, BUN, and BUN/Cr ratio, are valuable in differentiating between UGIB and LGIB. These parameters can serve as early evaluation indexes for GIB, facilitating timely intervention and treatment to enhance therapeutic outcomes.

摘要

背景

本研究通过关注血常规参数来区分上消化道出血和下消化道出血，以提高诊断精度，从而满足这一关键需求。

目的

本研究旨在确定和比较特定的血常规参数，以确定它们在区分上消化道出血和下消化道出血方面的功效，从而为临床决策提供改进。

方法

这是一项回顾性研究，分析了 2017 年 1 月至 2020 年 6 月期间我院收治的 119 例胃肠道出血（GIB）患者。其中 86 例诊断为上消化道出血（UGIB），33 例诊断为下消化道出血（LGIB）。入院后采集外周血样进行全血细胞计数检查，包括白细胞计数（WBC）、红细胞计数（RBC）、血红蛋白（Hb）、血小板计数（PLT）、血尿素氮（BUN）、肌酐（Cr）和 BUN/Cr 比值。比较 UGIB 和 LGIB 组之间血常规参数的差异。采用受试者工作特征（ROC）曲线分析评估血常规检查在区分 UGIB 和 LGIB 中的效果。

结果

研究显示，LGIB 和 UGIB 患者的 WBC 和 Cr 水平无显著差异（P >.05）。然而，与 LGIB 患者相比，UGIB 患者的 RBC、Hb 和 PLT 水平显著降低，BUN 和 BUN/Cr 比值水平显著升高（P <.05）。Pearson 相关系数分析表明，GIB 患者的 BUN/Cr 与 RBC、Hb 和 PLT 呈负相关，与 BUN 呈正相关（P <.05）。ROC 分析表明，RBC、Hb、PLT、BUN 和 BUN/Cr 比值在区分 UGIB 和 LGIB 方面有效（P <.05）。