Department of Ophthalmology, Infant Jesus Teaching Hospital, Medical University of Warsaw, Warsaw, Poland.
Department of Experimental and Clinical Physiology, Center for Preclinical Research, Medical University of Warsaw, Warsaw, Poland.
Eur J Ophthalmol. 2024 Nov;34(6):1655-1666. doi: 10.1177/11206721241237309. Epub 2024 Mar 3.
Physiological adaptation of the eye to the visual perception of near objects consists of the "near triad": convergence, accommodation, and pupil miosis. Normally, these tend to revert when one stops fixating on a near object. Spasm of the near reflex (SNR) is a pathological phenomenon, which manifests itself by the persistence of the above-mentioned adjustments, which prevents the eye from returning to its relaxed state. In this narrative review, we aim to summarize the etiology, diagnostics, treatment, and prevention of SNR. The literature review was performed by searching online databases. The clinical presentation of SNR is diverse; it presents as isolated accommodative spasm more frequently than impairment of all three components of the near triad. Patients usually present with fluctuations in visual acuity, blurred vision, diplopia, and asthenopia. The etiology is not fully understood. Potential causes include neuroanatomic, organic, and psychogenic disorders. The diagnosis is clinical, based on the constellation of symptoms and assessment of the near triad. The diagnostic golden standard is a cycloplegic examination of refraction, preferably using cyclopentolate hydrochloride (1%, 0.5%, or 0.1% solution). The first-line treatment requires the administration of a cycloplegic drug in combination with plus lenses, flipper lenses, optical fogging, or miotics. For secondary cases, causal treatment should be implemented. Prevention of SNR should be based on eliminating modifiable risk factors. We propose including screening for SNR symptoms in every ophthalmic examination, especially among patients with psychogenic or neural disorders, after brain trauma, or young adults spending much time in front of computer screens.
眼睛对近距物体视觉感知的生理适应包括“近距三联征”:集合、调节和瞳孔缩小。通常,当一个人停止注视近距物体时,这些反应会趋于恢复。近反射痉挛(SNR)是一种病理现象,表现为上述调节持续存在,阻止眼睛恢复放松状态。在这篇叙述性综述中,我们旨在总结 SNR 的病因、诊断、治疗和预防。文献综述通过在线数据库进行搜索。SNR 的临床表现多种多样;它表现为孤立性调节痉挛,比近距三联征的所有三个组成部分的损害更为常见。患者通常表现为视力波动、视力模糊、复视和视疲劳。病因尚不完全清楚。潜在的原因包括神经解剖学、器质性和心因性障碍。诊断基于症状组合和近距三联征评估,主要依靠临床诊断。诊断的金标准是使用盐酸环戊酯(1%、0.5%或 0.1%溶液)进行散瞳屈光检查。一线治疗需要使用散瞳药物联合正镜片、翻转镜、光学雾化或缩瞳剂。对于继发性病例,应实施病因治疗。SNR 的预防应基于消除可改变的危险因素。我们建议在每次眼科检查中都筛查 SNR 症状,尤其是在有心理或神经障碍、脑外伤或长时间在电脑屏幕前工作的年轻患者中。