Chakraborty Nikita, Rajbongshi Kamal K, Gondaliya Amisha, Patel Bhisma K
Department of Chemistry, Indian Institute of Technology Guwahati, 781039, Assam, India.
Department of Chemistry, Cotton University, Guwahati, 781001, Assam, India.
Org Biomol Chem. 2024 Mar 20;22(12):2375-2379. doi: 10.1039/d4ob00175c.
A visible-light-promoted, PIDA/I-mediated acylation of NH-sulfoximines with methylarenes as an acyl source has been achieved. This transition metal and photosensitizer-free approach provides easy access to -acylsulfoximines oxidative coupling of sulfoximines with easily available methylarenes without using any peroxide source. Mechanistic investigations suggest the intermediacy of radicals and the importance of molecular oxygen.
实现了以甲基芳烃为酰基源、可见光促进的PIDA/I介导的NH-亚砜亚胺酰化反应。这种无过渡金属和光敏剂的方法无需使用任何过氧化物源，就能通过亚砜亚胺与易得的甲基芳烃的氧化偶联轻松制得α-酰基亚砜亚胺。机理研究表明自由基的中间体性质以及分子氧的重要性。
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