Department of Shizuoka Physical Therapy, Faculty of Health Science, Tokoha University, Shizuoka, Japan.
Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan.
Geriatr Gerontol Int. 2024 Apr;24(4):378-384. doi: 10.1111/ggi.14849. Epub 2024 Mar 4.
The combination of dynapenia (age-related muscle weakness) and obesity is referred to as dynapenic obesity. We examined the associations between dynapenic obesity and cortical bone thickness and trabecular bone density.
The participants were 797 community-dwelling postmenopausal women (with an average age of 62.5 years) who were stratified into normopenia without obesity, dynapenia without obesity (dynapenia), normopenia with obesity (obesity) and dynapenia with obesity (dynapenia obesity) groups based on their grip strength and body fat percentage. Cortical bone thickness and trabecular bone density were measured using ultrasonic bone densitometry. The participants were further divided into those with low cortical bone thickness and low trabecular bone density. Logistic regression analysis was used to identify associated factors.
Individuals with dynapenia (odds ratio [OR] 1.77, 95% confidence interval [CI] 1.16-2.68), obesity (OR 2.46, 95% CI 1.62-3.75) and dynapenic obesity (OR 4.07, 95% CI 2.44-6.79) all significantly increased the odds of low cortical bone thickness. Conversely, the odds of low trabecular bone density were significantly lower in the obesity group (OR 0.65, 95% CI 0.43-0.99) and dynapenic obesity group (OR 0.60, 95% CI 0.37-0.97).
Dynapenic obesity was found to be associated with cortical bone thinning that might compromise bone health. Postmenopausal women with dynapenic obesity might need to be closely monitored for preserving bone health. Geriatr Gerontol Int 2024; 24: 378-384.
随着年龄的增长而出现的肌肉力量减弱（称为 dynapenia）与肥胖相结合，被称为 dynapenic 肥胖。我们研究了 dynapenic 肥胖与皮质骨厚度和小梁骨密度之间的关联。
参与者为 797 名居住在社区的绝经后女性（平均年龄 62.5 岁），根据握力和体脂百分比将她们分为非肥胖正常组、非肥胖 dynapenia 组（dynapenia）、肥胖正常组（肥胖）和 dynapenic 肥胖组（dynapenia 肥胖）。使用超声骨密度仪测量皮质骨厚度和小梁骨密度。参与者进一步分为皮质骨厚度和小梁骨密度均较低的人群。使用逻辑回归分析确定相关因素。
dynapenia（比值比 [OR] 1.77，95%置信区间 [CI] 1.16-2.68）、肥胖（OR 2.46，95% CI 1.62-3.75）和 dynapenic 肥胖（OR 4.07，95% CI 2.44-6.79）个体均显著增加了皮质骨厚度较低的几率。相反，肥胖组（OR 0.65，95% CI 0.43-0.99）和 dynapenic 肥胖组（OR 0.60，95% CI 0.37-0.97）的小梁骨密度较低的几率显著降低。
dynapenic 肥胖与皮质骨变薄有关，可能会影响骨骼健康。患有 dynapenic 肥胖的绝经后女性可能需要密切监测以维持骨骼健康。老年医学与老年病学国际 2024；24：378-384。
