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2019 年至 2023 年东非地区用于癌症管理的草药的综述。

Review of Herbal Medicinal Plants Used in the Management of Cancers in the East Africa Region from 2019 to 2023.

机构信息

Makerere University, Kampala, Uganda.

Islamic University in Uganda, Kampala, Uganda.

出版信息

Integr Cancer Ther. 2024 Jan-Dec;23:15347354241235583. doi: 10.1177/15347354241235583.

DOI:10.1177/15347354241235583
PMID:38445504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10916491/
Abstract

BACKGROUND

In the East African region, herbal plants are essential in the treatment and control of cancer. Given the diverse ecological and cultural makeup of the regional states, it is likely that different ethnic groups will use the same or different plants for the same or different diseases. However, since 2019, this has not been compiled into a single study.

PURPOSE

The study aimed to compile and record the medicinal plants utilized in East Africa from April 2019 to June 2023 to treat various cancer types.

MATERIALS AND METHODS

The study examined 13 original studies that included ethnobotanical research conducted in East Africa. They were retrieved from several internet databases, including Google Scholar, Scopus, PubMed/Medline, Science Direct, and Research for Life. The study retrieved databases on plant families and species, plant parts used, preparation methods and routes of administration, and the country where the ethnobotanical field surveys were conducted. Graphs were produced using the GraphPad Prism 8.125 program (GraphPad Software, Inc., San Diego, CA). Tables and figures were used to present the data, which had been condensed into percentages and frequencies.

RESULTS

A total of 105 different plant species from 45 different plant families were identified, including Asteraceae (14), Euphorbiaceae (12), Musaceae (8), and Apocynaceae (7). Uganda registered the highest proportion (46% of the medicinal plants used). The most commonly mentioned medicinal plant species in cancer management was . Herbs (32%), trees and shrubs (28%), and leaves (45%) constituted the majority of herbal remedies. Most herbal remedies were prepared by boiling (decoction) and taken orally (57%).

CONCLUSION

East Africa is home to a wide variety of medicinal plant species that local populations and herbalists, or TMP, frequently use in the treatment of various types of cancer. The most frequently used families are Asteraceae and Euphorbiaceae, with the majority of species being found in Uganda. The most frequently utilized plant species is . Studies on the effectiveness of against other malignancies besides prostate cancer are required.

摘要

背景

在东非地区,草药在癌症的治疗和控制中至关重要。鉴于该地区国家多样的生态和文化构成,不同的民族群体可能会使用相同或不同的植物来治疗相同或不同的疾病。然而,自 2019 年以来,这并没有被汇编成一项单一的研究。

目的

本研究旨在汇编和记录 2019 年 4 月至 2023 年 6 月期间东非用于治疗各种癌症类型的药用植物。

材料和方法

本研究检查了 13 项原始研究,这些研究包括在东非进行的民族植物学研究。它们是从几个互联网数据库中检索到的,包括谷歌学术、Scopus、PubMed/Medline、Science Direct 和生命研究。该研究检索了植物科和物种、使用的植物部位、制备方法和给药途径以及进行民族植物学实地调查的国家的数据库。图表是使用 GraphPad Prism 8.125 程序(GraphPad Software,Inc.,圣地亚哥,CA)制作的。表格和图表用于呈现数据,这些数据已被压缩为百分比和频率。

结果

共确定了来自 45 个不同植物科的 105 种不同的植物物种,包括菊科(14 种)、大戟科(12 种)、芭蕉科(8 种)和夹竹桃科(7 种)。乌干达的药用植物比例最高(占所用药用植物的 46%)。在癌症管理中最常被提及的药用植物物种是. 在癌症管理中最常被提及的药用植物物种是. 在癌症管理中最常被提及的药用植物物种是 。草药(32%)、树木和灌木(28%)和叶子(45%)构成了大多数草药疗法的主体。大多数草药疗法是通过煮沸(煎剂)和口服(57%)来制备的。

结论

东非拥有各种各样的药用植物物种,当地居民和草药医生,或 TMP,经常使用这些植物来治疗各种类型的癌症。最常用的科是菊科和大戟科,大多数物种都在乌干达发现。最常使用的植物物种是. 需要研究 对前列腺癌以外的其他恶性肿瘤的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/895caf92533e/10.1177_15347354241235583-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/11126e7967e0/10.1177_15347354241235583-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/28436df9b8be/10.1177_15347354241235583-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/16ba79343ab6/10.1177_15347354241235583-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/410c8488c179/10.1177_15347354241235583-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/3bca1dee77aa/10.1177_15347354241235583-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/3f87bfd77a1b/10.1177_15347354241235583-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/895caf92533e/10.1177_15347354241235583-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/11126e7967e0/10.1177_15347354241235583-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/28436df9b8be/10.1177_15347354241235583-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/16ba79343ab6/10.1177_15347354241235583-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/410c8488c179/10.1177_15347354241235583-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/3bca1dee77aa/10.1177_15347354241235583-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/3f87bfd77a1b/10.1177_15347354241235583-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7d8/10916491/895caf92533e/10.1177_15347354241235583-fig7.jpg

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