Hospital Naval Marcílio Dias (HNMD), Rio de Janeiro, RJ, Brasil.
Unidade de Pesquisa Urogenital, Universidade do Estado do Rio de Janeiro - Uerj, Rio de Janeiro, RJ, Brasil.
Int Braz J Urol. 2024 May-Jun;50(3):335-345. doi: 10.1590/S1677-5538.IBJU.2024.9909.
The superiority of the functional results of robot-assisted radical prostatectomyis still controversial. Despite this, it is known that minimally invasive surgery obtains better results when analyzing blood loss, blood transfusion and length of stay, for example. Several studies have analyzed the impact of the resident physician's involvement on the results of urological surgeries. The simple learning curve for robot-assisted radical prostate surgery is estimated to be around 10 to 12 cases. Learning curve data for robotic surgeons is heterogeneous, making it difficult to analyze. Rare studies compare the results of a radical prostatectomy of an inexperienced surgeon starting his training in open surgery, with the results of the same surgeon, a few years later, starting training in robotic surgery.
to analyze the results of open radical prostatectomy surgeries (ORP) performed by urology residents, comparing them to the results of robot-assisted radical prostatectomy (RARP), performed by these same surgeons, after completing their training in urology.
a retrospective analysis of the cases of only 3 surgeons was performed. 50 patients underwent ORP (group A). The surgeons who operated on the ORP patients were in the 3rd and final year of the urology residency program and beginners in ORP surgery, but with at least 4 years of experience in open surgery. The same surgeons, already trained urologists, began their training in robotic surgery and performed 56 RARP surgeries (group B). For the comparative analysis, data were collected on age, number of lymph nodes removed, surgery time, hospitalization time, drain volume, drain permanence time, indwelling bladdercateter (IBC) permanence time, positive surgical margin, biochemical recurrence, risk classification (ISUP), intra and postoperative complications, urinary incontinence (UI) and erectile dysfunction (ED). The console used was the Da Vinci Si, from Intuitive®. For statistical analysis, the Shapiro-Wilk test verified that the data did not follow normality, the Levene test guaranteed homogeneity, and the Mann-Whitney test performed the comparative analysis of the quantitative data. For the analysis of qualitative data, the Chi-square test was used for nominal variables and the Mann-Whitney U test for ordinal variables. Additionally, the Friedman test analyzed whether there was an improvement in the perception of UI or ED over the months, for each group individually (without comparing them), and the post-hoc Durbin-Conover test, for the results with statistically significant difference. We used a p-value < 0.05, and the Jamovi® program (Version 2.0).
there was no statistically significant difference between the groups for age, number of lymph nodes removed, positive surgical margin, biochemical recurrence, risk classification and urinary incontinence. Additionally, we observed that the surgical time was longer in group B. On the other hand, the length of stay, drain volume, drain time, IBC time, complication rate and levels of erectile dysfunction in the third and sixth months were higher in group A, when compared to group B. We also observed that there was no evolutionary improvement in ED over the months in both groups, and that there was a perception of improvement in UI from the 1st to the 3rd month in group A, and from the 1st to the 6th month, and from the 3rd to the 12th month, in group B.
the learning curve of RARP is equivalent to the curve of ORP. In general, the results for the robotic group were better, however, the functional results were similar between the groups, with a slight tendency of advantage for the robotic arm.
机器人辅助根治性前列腺切除术的功能结果优越性仍存在争议。尽管如此,人们知道微创手术在分析出血量、输血和住院时间等方面可以获得更好的结果。已经有几项研究分析了住院医师参与对泌尿科手术结果的影响。机器人辅助根治性前列腺切除术的简单学习曲线估计约为 10 到 12 例。机器人外科医生的学习曲线数据存在异质性,难以进行分析。很少有研究比较经验不足的外科医生在开始接受开放手术培训时进行根治性前列腺切除术的结果,以及同一位外科医生在几年后开始接受机器人手术培训时的结果。
分析泌尿科住院医师进行的开放根治性前列腺切除术(ORP)的结果,并将其与同一外科医生在完成泌尿科培训后进行的机器人辅助根治性前列腺切除术(RARP)的结果进行比较。
对仅 3 位外科医生的病例进行了回顾性分析。50 例患者接受了 ORP(A 组)。进行 ORP 手术的外科医生处于泌尿科住院医师培训的第 3 年和最后一年,并且是 ORP 手术的初学者,但至少有 4 年的开放手术经验。同一位外科医生,已经接受过泌尿科培训,开始接受机器人手术培训,并进行了 56 例 RARP 手术(B 组)。为了进行比较分析,收集了年龄、切除的淋巴结数量、手术时间、住院时间、引流量、引流时间、留置导尿管时间、阳性切缘、生化复发、风险分类(ISUP)、术中及术后并发症、尿失禁(UI)和勃起功能障碍(ED)等数据。使用的控制台是 Intuitive®的 Da Vinci Si。为了进行统计分析,Shapiro-Wilk 检验验证数据不符合正态分布,Levene 检验保证了同质性,Mann-Whitney 检验进行了定量数据的比较分析。对于定性数据的分析,使用卡方检验进行名义变量分析,Mann-Whitney U 检验进行有序变量分析。此外,Friedman 检验分析了每个组(不进行比较)的 UI 或 ED 是否在几个月内得到改善,以及在具有统计学意义差异的结果中,使用 Durbin-Conover 检验进行事后检验。我们使用 p 值<0.05 和 Jamovi®程序(版本 2.0)。
两组在年龄、切除的淋巴结数量、阳性切缘、生化复发、风险分类和尿失禁方面没有统计学差异。此外,我们观察到 B 组的手术时间较长。另一方面,A 组的住院时间、引流量、引流时间、留置导尿管时间、并发症发生率和勃起功能障碍在第 3 个月和第 6 个月的水平更高。我们还观察到,两组 ED 在几个月内都没有得到改善,并且 A 组的 UI 在第 1 个月到第 3 个月、第 1 个月到第 6 个月以及第 3 个月到第 12 个月之间都有改善,而 B 组则在第 1 个月到第 3 个月、第 1 个月到第 6 个月和第 3 个月到第 6 个月之间都有改善。
RARP 的学习曲线与 ORP 的学习曲线相当。总的来说,机器人组的结果更好,然而,两组的功能结果相似,机器人手臂有轻微的优势。