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比较可触及未降睾丸的阴囊和腹股沟或经皮睾丸固定术:随机对照试验的荟萃分析。

Comparison of scrotal and inguinal orchiopexy for palpable undescended testis: a meta-analysis of randomized controlled trials.

机构信息

Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jalan Diponegoro No. 71, Jakarta, 10430, Indonesia.

出版信息

Pediatr Surg Int. 2024 Mar 7;40(1):74. doi: 10.1007/s00383-024-05655-7.

Abstract

INTRODUCTION

Scrotal and inguinal orchiopexy are two commonly used surgical approaches for palpable undescended testis (UDT), each with distinct advantages. However, the optimal approach remains a matter of debate, warranting a comprehensive meta-analysis of randomized controlled trials (RCTs) to guide clinical decision-making.

MATERIALS AND METHODS

A comprehensive literature search was conducted, adhering to PRISMA guidelines, to select RCTs comparing scrotal and inguinal orchiopexy for palpable UDT. Eight RCTs were selected for meta-analysis. Outcome measures included operative time, hospitalization duration, total complications, wound infection or dehiscence, testicular atrophy or hypotrophy, and testicular re-ascent rate. The evaluation of the study's quality was conducted by utilizing the revised Cochrane risk-of-bias tool.

RESULTS

Scrotal orchiopexy showed significantly shorter operative time compared to the inguinal approach (WMD: - 15.06 min; 95% CI: - 21.04 to - 9.08). However, there was no significant difference in hospitalization duration (WMD: - 0.72 days; 95% CI: - 1.89-0.45), total complications (OR: 1.08; 95% CI: 0.70-1.66), wound infection or dehiscence (OR: 0.73; 95% CI: 0.27-1.99), testicular atrophy or hypotrophy (OR: 1.03; 95% CI: 0.38-2.78), and testicular re-ascent (OR: 1.43; 95% CI: 0.67-3.06) between the two approaches. A small proportion of cases (7.3%) required conversion from scrotal to inguinal orchiopexy due to specific anatomical challenges.

CONCLUSION

Both scrotal and inguinal orchiopexy are safe and effective for palpable UDT, with comparable outcomes in terms of hospitalization and complications. Scrotal orchiopexy offers the advantage of shorter operative time. Clinicians can use this evidence to make informed decisions on the surgical approach for palpable UDT.

摘要

引言

阴囊和腹股沟入路的睾丸固定术是治疗可触及未降睾丸(UDT)的两种常用手术方法,各有其优势。然而,哪种方法是最佳选择仍存在争议,因此需要对随机对照试验(RCT)进行全面的荟萃分析,以指导临床决策。

材料和方法

我们按照 PRISMA 指南进行了全面的文献检索,以选择比较阴囊和腹股沟入路的睾丸固定术治疗可触及 UDT 的 RCT。共选择了 8 项 RCT 进行荟萃分析。结局指标包括手术时间、住院时间、总并发症、伤口感染或裂开、睾丸萎缩或发育不良、睾丸再下降率。使用修订后的 Cochrane 偏倚风险工具评估研究质量。

结果

与腹股沟入路相比,阴囊入路的手术时间明显更短(WMD:-15.06 分钟;95%CI:-21.04 至-9.08)。然而,两种方法的住院时间(WMD:-0.72 天;95%CI:-1.89 至-0.45)、总并发症(OR:1.08;95%CI:0.70 至 1.66)、伤口感染或裂开(OR:0.73;95%CI:0.27 至 1.99)、睾丸萎缩或发育不良(OR:1.03;95%CI:0.38 至 2.78)和睾丸再下降(OR:1.43;95%CI:0.67 至 3.06)方面无显著差异。由于特定的解剖学挑战,少数(7.3%)病例需要从阴囊入路转为腹股沟入路。

结论

阴囊和腹股沟入路的睾丸固定术对可触及 UDT 均安全有效,在住院时间和并发症方面的结果相当。阴囊入路的优势在于手术时间更短。临床医生可以根据本研究证据,对可触及 UDT 的手术方法做出明智决策。

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