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下行性坏死性纵隔炎:儿童中的一种罕见病症。

Descending necrotising mediastinitis: a rare entity in children.

作者信息

Marques Davide Lourenço, Rato Catarina, Miguéis António, Miguéis Jorge

机构信息

Department of Otorhinolaryngology, Coimbra University Hospital Centre, Coimbra, Portugal

Department of Otorhinolaryngology, Coimbra University Hospital Centre, Coimbra, Portugal.

出版信息

BMJ Case Rep. 2024 Mar 7;17(3):e258304. doi: 10.1136/bcr-2023-258304.

Abstract

We present a case of descending necrotising mediastinitis (DNM) originating from a retropharyngeal abscess in a healthy early childhood patient. The patient had a history of fever, odynophagia and refusal to eat, followed by rapid deterioration of the clinical state. Cervicothoracic CT was performed, which revealed a right parapharyngeal abscess, extending to the mediastinum and occupying the retropharyngeal/visceral space, with gaseous content throughout this collection, associated with bilateral pleural effusion, aspects compatible with DNM. She started broad-spectrum antibiotic therapy and transoral drainage of the parapharyngeal and retropharyngeal collections was performed under general anaesthesia. She was admitted to the intensive care unit. The patient showed clinical, analytical and imaging improvement, having been transferred to the ear, nose and throat department, with favourable evolution. Early diagnosis of DNM by cervicothoracic CT and multidisciplinary approaches, including intensive care, broad-spectrum antibiotics and surgical intervention, are crucial to minimise the morbidity and mortality.

摘要

我们报告一例健康幼儿患者因咽后脓肿引发下行性坏死性纵隔炎(DNM)的病例。该患者有发热、吞咽痛和拒食史,随后临床状态迅速恶化。进行了颈胸CT检查,结果显示右侧咽旁脓肿,延伸至纵隔并占据咽后/内脏间隙,该积液内有气体成分,伴有双侧胸腔积液,这些表现符合DNM。患者开始接受广谱抗生素治疗,并在全身麻醉下经口引流咽旁和咽后积液。她被收入重症监护病房。患者在临床、分析和影像学方面均有改善,随后转至耳鼻喉科,病情进展良好。通过颈胸CT早期诊断DNM以及采用多学科方法,包括重症监护、广谱抗生素和手术干预,对于降低发病率和死亡率至关重要。

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