眼后段手术后继发毒性前节综合征的爆发：一项回顾性分析。
Outbreak of toxic anterior segment syndrome following vitreoretinal surgery - A retrospective analysis.
机构信息
Department of Vitreoretinal Services, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
Chief Medical Officer, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
出版信息
Indian J Ophthalmol. 2024 Jun 1;72(6):860-863. doi: 10.4103/IJO.IJO_1867_23. Epub 2024 Mar 8.
BACKGROUND
Toxic anterior segment syndrome (TASS) is an uncommon complication of vitreoretinal surgery and is characterized by severe anterior chamber reaction, hypopyon, and limbus-to-limbus corneal edema.
METHODS
Twenty-nine vitreoretinal surgeries were performed, of which 14 developed TASS in the early postoperative period. The operative records were reviewed retrospectively.
RESULTS
The median age of patients was 49.07 ± 16.75 years and 14.28% of them were female. Also, 71.42% were operated in the left eye and 42.8% were pseudophakic. Recurrent retinal detachment, secondary scleral-fixating intraocular lens (SFIOL), and silicone oil removal (SOR) were the most common procedures. Severe anterior chamber reaction was seen in 14 patients, circumcorneal congestion in eight, corneal edema in 11 (78.6%), hypopyon in 13 (92.8%), and severe fibrin membrane in two patients.
CONCLUSION
We describe the largest series of TASS following uneventful vitreoretinal surgery. Balanced salt solution was the instigating agent in this series. A prompt and thorough investigation is critical in obviating recurrences.
背景
毒性前节综合征（TASS）是玻璃体视网膜手术后罕见的并发症，其特征为严重的前房反应、前房积脓和角膜缘到角膜缘水肿。
方法
共进行了 29 例玻璃体视网膜手术，其中 14 例在术后早期发生 TASS。回顾性分析手术记录。
结果
患者的中位年龄为 49.07 ± 16.75 岁，女性占 14.28%。71.42%的患者左眼接受手术，42.8%为人工晶状体眼。最常见的手术是复发性视网膜脱离、二期巩膜固定型人工晶状体（SFIOL）和硅油取出术（SOR）。14 例患者出现严重的前房反应，8 例患者出现角膜环行充血，11 例（78.6%）患者出现角膜水肿，13 例（92.8%）患者出现前房积脓，2 例患者出现严重的纤维蛋白膜。
结论
我们描述了一系列玻璃体视网膜手术后发生 TASS 的最大系列病例。在本系列中，平衡盐溶液是引发 TASS 的原因。及时彻底的调查对于避免复发至关重要。
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