Shlian Daniel G, Summers Rachael H, Martinez Katelyn, Upmacis Rita K
Department of Chemistry, Columbia University, New York, NY 10027, USA.
Department of Chemistry & Physical Sciences, Pace University, New York, NY 10038, USA.
Acta Crystallogr E Crystallogr Commun. 2024 Feb 27;80(Pt 3):335-338. doi: 10.1107/S205698902400166X. eCollection 2024 Mar 1.
Metal complexes of 3,5-diiso-propyl-salicylate are reported to have anti-inflammatory and anti-convulsant activities. The title binuclear copper complex, [Cu(CHO)(CHOS)] or [Cu(II)(3,5-DIPS)(DMSO)], contains two five-coordinate copper atoms that are bridged by four 3,5-diiso-propyl-salicylate ligands and capped by two axial dimethyl sulfoxide (DMSO) moieties. Each copper atom is attached to four oxygen atoms in an almost square-planar fashion, with the addition of a DMSO ligand in an apical position leading to a square-pyramidal arrangement. The hy-droxy group of the diiso-propyl-salicylate ligands participates in intra-molecular O-H⋯O hydrogen-bonding inter-actions.
据报道,3,5-二异丙基水杨酸的金属配合物具有抗炎和抗惊厥活性。标题双核铜配合物[Cu(CHO)(CHOS)]或[Cu(II)(3,5-DIPS)(DMSO)]包含两个五配位铜原子,它们由四个3,5-二异丙基水杨酸配体桥联,并由两个轴向二甲基亚砜(DMSO)部分封端。每个铜原子以几乎平面正方形的方式与四个氧原子相连,在顶端位置添加一个DMSO配体导致形成四方锥排列。二异丙基水杨酸配体的羟基参与分子内O-H⋯O氢键相互作用。