Department of Medical Laboratory Techniques, Al-Maarif University College, Al-Anbar, Iraq.
Department of Obstetry and Ginecology, Lambung Mangkurat University Banjarmasin, Indonesia.
Pathol Res Pract. 2024 Apr;256:155218. doi: 10.1016/j.prp.2024.155218. Epub 2024 Feb 17.
Cancer remains one of the most pressing health challenges globally, necessitating ongoing research into innovative therapeutic approaches. This article explores two critical factors influencing cancer: ncRNAs and nanotherapy. The role of ncRNAs, including microRNAs and long non-coding RNAs, in cancer pathogenesis, progression, and treatment resistance is elucidated. Additionally, the potential of nanotherapy, leveraging nanoscale materials for targeted drug delivery and enhanced therapeutic efficacy, is investigated. By comprehensively analyzing the molecular mechanisms underlying ncRNA dysregulation and the promise of nanotherapy in cancer treatment, this article aims to provide valuable insights into novel therapeutic strategies for combating cancer.
癌症仍然是全球最紧迫的健康挑战之一，需要不断研究创新的治疗方法。本文探讨了影响癌症的两个关键因素：ncRNAs 和纳米疗法。阐述了 ncRNAs（包括 microRNAs 和长非编码 RNA）在癌症发病机制、进展和治疗耐药性中的作用。此外，还研究了纳米疗法的潜力，利用纳米级材料进行靶向药物输送和提高治疗效果。通过全面分析 ncRNA 失调的分子机制和纳米疗法在癌症治疗中的前景，本文旨在为对抗癌症的新治疗策略提供有价值的见解。
