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眼外肌神经麻痹的手术治疗:比较外直肌去神经术联合内直肌切除术或内直肌固定于内眦韧带来治疗。

Surgical management of oculomotor nerve palsy: a comparison of lateral rectus deactivation combined with either medial rectus resection or medial rectus fixation to the medial palpebral ligament.

机构信息

Department of Paediatric Ophthalmology and Adult Strabismus, Aravind Eye Hospital, Madurai, India.

Department of Paediatric Ophthalmology and Adult Strabismus, Aravind Eye Hospital, Madurai, India.

出版信息

J AAPOS. 2024 Apr;28(2):103871. doi: 10.1016/j.jaapos.2024.103871. Epub 2024 Mar 7.

Abstract

PURPOSE

To analyze and compare the outcome of two different surgical procedures in patients with complete oculomotor nerve palsy with large-angle exotropia.

METHODS

The medical records of patients with total oculomotor nerve palsy and large-angle exotropia operated on at a single center from January 2006 to June 2020 were reviewed retrospectively. One group underwent lateral rectus deactivation with medial rectus resection (resection group); the other group underwent lateral rectus deactivation with medial rectus fixation to the medial palpebral ligament (fixation group). Surgical outcomes on the first postoperative day and at 6 months postoperatively were analyzed, including alignment and postoperative complications. All statistical analyses were performed using STATA version 14. A P value of <0.05 was considered significant.

RESULTS

A total of 35 patients were included. There was a trend toward greater surgical success in the fixation group (93%) than in the resection group (65%), but these results were not statistically significant. Postoperative exotropic drifts were noted in both the procedures but tended to be more with patients in the resection group. Postoperative complications were noted only in the fixation group.

CONCLUSIONS

Lateral rectus deactivation with medial rectus fixation to the medial palpebral ligament requires more time and greater surgical expertise but appears to better prevent postoperative exotropic drift compared with lateral rectus deactivation combined with medial rectus resection.

摘要

目的

分析和比较伴有大角度外斜视的完全动眼神经麻痹患者两种不同手术方法的结果。

方法

回顾性分析 2006 年 1 月至 2020 年 6 月在单中心接受手术治疗的完全动眼神经麻痹和大角度外斜视患者的病历。一组行外直肌去神经化联合内直肌部分切除术(切除术组);另一组行外直肌去神经化联合内直肌固定于内眦韧带(固定组)。分析两组患者术后第 1 天和术后 6 个月的眼位和术后并发症。所有统计分析均采用 STATA 版本 14 进行。P 值<0.05 为差异有统计学意义。

结果

共纳入 35 例患者。固定组(93%)的手术成功率有高于切除术组(65%)的趋势,但差异无统计学意义。两种术式术后均有外斜视漂移,但切除术组更为明显。固定组术后出现并发症。

结论

与外直肌去神经化联合内直肌部分切除术相比,外直肌去神经化联合内直肌固定于内眦韧带需要更多的时间和更高的手术技巧,但似乎能更好地预防术后外斜视漂移。

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