Department of Neurology, Asahikawa City Hospital, Japan.
Department of Radiology, Asahikawa City Hospital, Japan.
Intern Med. 2024 Nov 1;63(21):2895-2901. doi: 10.2169/internalmedicine.3243-23. Epub 2024 Mar 11.
Objective We aimed to investigate the relationship between tortuosity of the extracranial internal carotid artery (ICA) or vertebral artery (VA) and vascular risk factors among residents of Asahikawa, northeast Japan. Methods We retrospectively surveyed participants of "brain dock" medical brain checkups, which involved magnetic resonance imaging and angiography. We measured the tortuosity of the ICA and VA, and evaluated vascular risk factors based on medical interviews, questionnaires, and medical records. Results A total of 218 participants were enrolled in the study. ICA tortuosity (right and left) was significantly correlated with age [odds ratio (OR): 2.452, 95% confidence interval (CI): 1.695-3.548, p<0.001]. A more pronounced correlation was observed in females than in males (OR: 1.678, 95% CI: 1.004-2.807, p=0.048). VA tortuosity (right and left) was significantly correlated with age (OR: 1.786, 95% CI: 1.250-2.550, p=0.001) and smoking history (OR: 2.140, 95% CI: 1.235-3.707, p=0.007), and was more pronounced in females than in males (OR: 1.864, 95% CI: 1.107-3.137, p=0.019). Conclusion ICA tortuosity was correlated with age, while VA tortuosity was correlated with age and smoking history. ICA and VA tortuosity were more pronounced in females than in males.
本研究旨在探讨日本北海道旭川市居民的颅外颈内动脉(ICA)或椎动脉(VA)迂曲与血管危险因素之间的关系。
我们回顾性调查了参加“脑码头”医学脑检查的参与者,该检查包括磁共振成像和血管造影。我们测量了 ICA 和 VA 的迂曲程度,并根据医学访谈、问卷调查和病历评估了血管危险因素。
共有 218 名参与者纳入本研究。ICA 迂曲(左右)与年龄显著相关[优势比(OR):2.452,95%置信区间(CI):1.695-3.548,p<0.001]。女性的相关性更为显著(OR:1.678,95%CI:1.004-2.807,p=0.048)。VA 迂曲(左右)与年龄显著相关(OR:1.786,95%CI:1.250-2.550,p=0.001)和吸烟史(OR:2.140,95%CI:1.235-3.707,p=0.007),女性的相关性更为显著(OR:1.864,95%CI:1.107-3.137,p=0.019)。
ICA 迂曲与年龄相关,而 VA 迂曲与年龄和吸烟史相关。ICA 和 VA 迂曲在女性中更为显著。