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分析颞下颌关节紊乱疼痛的危险因素和相互作用:一项横断面研究。

Analysis of risk factors and interactions for pain in temporomandibular disorder: A cross-sectional study.

机构信息

Department of Rehabilitation Medicine, The Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai, China.

出版信息

J Oral Rehabil. 2024 Jul;51(7):1113-1122. doi: 10.1111/joor.13682. Epub 2024 Mar 15.

Abstract

BACKGROUND

Risk factors for temporomandibular disorder (TMD) pain remain unclear.

OBJECTIVES

This study aimed to identify risk factors for TMD pain using a biopsychosocial model and to investigate interactions between potential risk factors-oral behaviours (OBs), psychological factors and sleep quality-and their direct and indirect effects on TMD pain.

METHODS

This was a cross-sectional study of 488 patients with TMDs (422 women; 30.8 ± 9.4 years). Pain was assessed using the Numerical Rating Scale. Demographic, behavioural, psychological and biomedical data were collected through clinical examination, face-to-face interviews and questionnaires. Multiple linear regression analysis was used to identify factors associated with TMD pain. Mediation and moderation analysis were used to evaluate interactions between variables. Significant mediation ('0' not included in the 95% confidence interval (CI)) and moderation (p < .05) effects on TMD pain were identified.

RESULTS

Marital status, diagnosis subgroup, previous medication use, depression and sleep quality were significant risk factors for TMD pain (p < .05). Significant mediation effects were observed as follows: depression and sleep quality mediated the association between OBs and pain; sleep quality mediated the association between somatization, depression, anxiety and pain; and depression mediated the association between sleep quality and pain (all 95% CI did not contain '0').

CONCLUSIONS

(1) Marital status, diagnosis subgroup, previous medication use, depression and sleep quality were associated with TMD pain. (2) OBs can exacerbate pain by promoting depression and reducing sleep quality. Psychological factors and sleep quality can interact to exacerbate pain.

摘要

背景

颞下颌关节紊乱病(TMD)疼痛的危险因素仍不清楚。

目的

本研究旨在使用生物心理社会模型确定 TMD 疼痛的危险因素,并探讨潜在危险因素-口腔行为(OBs)、心理因素和睡眠质量之间的相互作用及其对 TMD 疼痛的直接和间接影响。

方法

这是一项横断面研究,共纳入 488 例 TMD 患者(422 名女性,30.8±9.4 岁)。疼痛采用数字评分量表进行评估。通过临床检查、面对面访谈和问卷调查收集人口统计学、行为、心理和生物医学数据。采用多元线性回归分析确定与 TMD 疼痛相关的因素。采用中介和调节分析评估变量之间的相互作用。确定了对 TMD 疼痛具有显著中介(“0”不包含在 95%置信区间(CI)内)和调节(p<.05)作用的因素。

结果

婚姻状况、诊断亚组、既往用药、抑郁和睡眠质量是 TMD 疼痛的显著危险因素(p<.05)。观察到显著的中介效应:抑郁和睡眠质量中介了 OBs 与疼痛之间的关系;睡眠质量中介了躯体化、抑郁、焦虑与疼痛之间的关系;抑郁中介了睡眠质量与疼痛之间的关系(所有 95%CI 均不包含“0”)。

结论

(1)婚姻状况、诊断亚组、既往用药、抑郁和睡眠质量与 TMD 疼痛有关。(2)OBs 可通过促进抑郁和降低睡眠质量加重疼痛。心理因素和睡眠质量可相互作用加重疼痛。

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