Ghandour Samir, Taseh Atta, Sussman Walter, Guss Daniel, Ashkani-Esfahani Soheil, Gupta Ashim, Waryasz Gregory
Foot & Ankle Research and Innovation Laboratory (FARIL), Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Good Samaritan Medical Center, Boston Sports & Biologics PC, Wellesley, MA, United States.
Front Pain Res (Lausanne). 2024 Feb 29;5:1254216. doi: 10.3389/fpain.2024.1254216. eCollection 2024.
Intra-articular injections are commonly used to manage joint pathologies, including osteoarthritis. While conventional ultrasound (US) guidance has generally improved intra-articular injection accuracy, forefoot and midfoot joint interventions are still often performed without imaging guidance. This pilot study aims to evaluate the efficacy of office-based, portable ultrasound (P-US) guided intra-articular injections for forefoot and midfoot joint pain caused by various degenerative pathologies.
A retrospective analysis was conducted on a series of consecutive patients who underwent P-US guided intra-articular injections following a chief complaint of forefoot or midfoot joint pain. Patients reported their pain levels using the Visual Analog Scale (VAS) pre-injection and at 3 months follow-up. The procedure was performed by an experienced foot and ankle surgeon using a linear array transducer for guidance, and a 25-gauge needle was used to inject a combination of 2 cc 1% lidocaine and 12 cc of Kenalog (40 mg/ml). Complications and pain scores were analyzed using a paired -test and < 0.05 was considered significant.
We included 16 patients, 31% male and 69% female with a mean age (±SD) of 61.31 (±12.04) years. None of the patients experienced immediate complications following the intervention. The mean pre-injection VAS score was significantly reduced from 5.21 (±2.04) to a mean of 0.50 (±1.32) at 3 months follow-up ( < 0.001). Thirteen patients reported complete resolution of pain at the 3-month follow-up. No adverse events were reported throughout the duration of the study.
This pilot study suggests P-US-guided intra-articular injections offer a safe and effective method for managing forefoot and midfoot joint pain caused by various arthritic pathologies. Further research is warranted to establish the long-term efficacy and comparative effectiveness of P-US-guided injections in larger patient cohorts as compared to non-image guided injections.
关节内注射常用于治疗包括骨关节炎在内的关节疾病。虽然传统超声(US)引导一般提高了关节内注射的准确性,但前足和中足关节干预仍常常在没有影像引导的情况下进行。这项初步研究旨在评估基于门诊的便携式超声(P-US)引导下关节内注射治疗由各种退行性病变引起的前足和中足关节疼痛的疗效。
对一系列因前足或中足关节疼痛主诉而接受P-US引导下关节内注射的连续患者进行回顾性分析。患者在注射前和随访3个月时使用视觉模拟量表(VAS)报告其疼痛程度。该操作由一位经验丰富的足踝外科医生使用线性阵列换能器进行引导,并用25号针头注射2 cc 1%利多卡因和12 cc曲安奈德(40 mg/ml)的混合液。使用配对t检验分析并发症和疼痛评分,P < 0.05被认为具有显著性。
我们纳入了16例患者,男性占31%,女性占69%,平均年龄(±标准差)为61.31(±12.04)岁。干预后没有患者出现即刻并发症。注射前VAS评分均值从5.21(±2.04)显著降低至随访3个月时的均值0.50(±1.32)(P < 0.001)。13例患者在随访3个月时报告疼痛完全缓解。在研究期间未报告不良事件。
这项初步研究表明,P-US引导下关节内注射为治疗由各种关节炎病变引起的前足和中足关节疼痛提供了一种安全有效的方法。与非影像引导注射相比,有必要进行进一步研究以确定P-US引导注射在更大患者队列中的长期疗效和相对有效性。