Wenyan Xu, Lifeng Yue, Jing Wu, Hui Jiang
Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Department of Otolaryngology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Front Neurol. 2024 Feb 29;15:1369193. doi: 10.3389/fneur.2024.1369193. eCollection 2024.
To analyze and compare the vestibular function of posterior canal cupulolithiasis and canalolithiasis.
The results of posterior cupulolithiasis in 45 cases, posterior canalolithiasis in 122 cases and 19 healthy controls were analyzed retrospectively.
The abnormal rates of vHIT in the canalolithiasis group and the cupulolithiasis group were 42.6 and 37.8%, respectively, both higher than those in the control group (both < 0.05); there was no statistically significant difference between two BPPV groups ( = 0.573). The abnormal vHIT in 76.9% of the canalolithiasis cases and 82.4% of the cupulolithiasis cases showed normal gain with saccades, with no difference between the groups ( = 0.859). The lesion location of vHIT in the two groups did not show a correlation with the affected side of BPPV (both > 0.05). 84.4% of canalolithiasis and 65.0% of cupulolithiasis had abnormal VEMP results, with no significant differences in abnormality rates or sides (both > 0.05). Abnormal results of VEMPs did not show any correlation with side ( > 0.05). The results of pc-ca and pc-cu were both abnormal in 14 cases and 7 cases, and there was no correlation between the site and side of the injury (all > 0.05).
The results of vHIT and VEMP in pc-cu and pc-ca were partially abnormal, but they did not show any correlation with side of BPPV. It can be considered that there are scattered vestibular peripheral organ damage in both groups.
分析并比较后半规管壶腹嵴顶耳石症和管结石症的前庭功能。
回顾性分析45例后半规管壶腹嵴顶耳石症、122例后半规管管结石症患者及19例健康对照者的结果。
管结石症组和壶腹嵴顶耳石症组视频头脉冲试验（vHIT）异常率分别为42.6%和37.8%，均高于对照组（均P＜0.05）；两组良性阵发性位置性眩晕（BPPV）患者之间差异无统计学意义（P = 0.573）。76.9%的管结石症患者和82.4%的壶腹嵴顶耳石症患者vHIT异常时扫视增益正常，两组间差异无统计学意义（P = 0.859）。两组vHIT病变部位与BPPV患侧无相关性（均P＞0.05）。84.4%的管结石症患者和65.0%的壶腹嵴顶耳石症患者前庭诱发肌源性电位（VEMP）结果异常，异常率及患侧差异均无统计学意义（均P＞0.05）。VEMP异常结果与患侧无相关性（P＞0.05）。后半规管-嵴顶（pc-ca）和后半规管-壶腹嵴顶（pc-cu）结果均异常的分别有14例和7例，损伤部位与患侧无相关性（均P＞0.05）。
后半规管壶腹嵴顶耳石症和后半规管管结石症患者vHIT和VEMP结果部分异常，但与BPPV患侧无相关性。可认为两组均存在散在的前庭外周器官损害。
