Huang Jia, Yin Lianhua, Li Xia, Xie Qiurong, He Youze, Wu Lijuan, Ni Xuling, Liu Zhizhen, Tao Liyuan, Tao Jing, Chen Lidian
Author Affiliations: College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China (Dr Huang, Mss Li and Xie, and Mr He); The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China (Dr Yin and Mss Wu and Ni); College of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China (Ms Li); National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China (Dr Liu); Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China (Dr L. Tao); and Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China (Drs J. Tao and Chen).
J Cardiopulm Rehabil Prev. 2024 May 1;44(3):212-218. doi: 10.1097/HCR.0000000000000856. Epub 2024 Mar 15.
Cardiorespiratory fitness (CRF) is a strong predictor of cardiorespiratory diseases and varies by race. The purpose of this study was to provide CRF reference standards and a prediction equation for peak oxygen uptake (V˙O 2peak ) from treadmill-based cardiopulmonary exercise testing (CPX) in Chinese individuals.
Healthy participants (n = 4199) who completed a CPX using a treadmill were studied. The percentiles of V˙O 2peak were determined for four age groups (decades). A regression prediction model was developed from the derivation cohort (n = 3361), validated in the independent validation cohort (n = 838), and compared with the widely used Wasserman equation and the Fitness Registry and the Importance of Exercise National Database (FRIEND) equation.
The mean V˙O 2peak values of four age groups (20-29, 30-39, 40-49, and 50-59 yr) were 42.6, 41.2, 38.7, and 35.9 mL/kg/min, respectively, for men, and 37.1, 34.7, 32.0, and 30.3 mL/kg/min, respectively, for women. The 50th percentiles of relative V˙O 2peak decreased with age for both sexes. The prediction equation was: Absolute V˙O 2peak (mL/min) = 236.68 - (504.64 × sex [male = 0; female = 1]) + (21.23× weight [kg]) - (14.31 × age [yr]) + (9.46 × height [cm]) (standard error of the estimate = 379.59 mL/min, R2 = 0.66, P < .001).Percentage predicted V˙O 2peak for the validation sample was 100.2%. The novel equation performed better than the other two equations.
This study reports the first CRF reference standards and prediction equation generated from treadmill CPX in China. These reference standards provide a framework for interpreting the CRF of the Chinese population and could be useful information for a global CRF database.
心肺适能（CRF）是心肺疾病的有力预测指标，且因种族而异。本研究旨在提供基于跑步机的心肺运动试验（CPX）得出的中国人群峰值摄氧量（V˙O₂peak）的CRF参考标准和预测方程。
对使用跑步机完成CPX的4199名健康参与者进行了研究。确定了四个年龄组（以十年计）的V˙O₂peak百分位数。从推导队列（n = 3361）建立回归预测模型，并在独立验证队列（n = 838）中进行验证，然后与广泛使用的瓦瑟曼方程以及健身注册与运动重要性国家数据库（FRIEND）方程进行比较。
四个年龄组（20 - 29岁、30 - 39岁、40 - 49岁和50 - 59岁）男性的平均V˙O₂peak值分别为42.6、41.2、38.7和35.9 mL/kg/min，女性分别为37.1、34.7、32.0和30.3 mL/kg/min。两性的相对V˙O₂peak的第50百分位数均随年龄下降。预测方程为：绝对V˙O₂peak（mL/min）= 236.68 - （504.64×性别[男性 = 0；女性 = 1]）+ （21.23×体重[kg]） - （14.31×年龄[岁]）+ （9.46×身高[cm]）（估计标准误 = 379.59 mL/min，R² = 0.66，P <.001）。验证样本的预测V˙O₂peak百分比为100.2%。新方程的表现优于其他两个方程。
本研究报告了中国首个基于跑步机CPX得出的CRF参考标准和预测方程。这些参考标准为解读中国人群的CRF提供了框架，可能是全球CRF数据库的有用信息。
