免疫治疗在食管胃结合部癌中的进展。
Advances in Immunotherapy in Esophagogastric Cancer.
机构信息
Division of Medical Oncology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Division of Medical Oncology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
出版信息
Hematol Oncol Clin North Am. 2024 Jun;38(3):599-616. doi: 10.1016/j.hoc.2024.02.002. Epub 2024 Mar 15.
Immune checkpoint inhibitors are rapidly transforming the care of patients with esophagogastric cancer. Particularly, anti-PD-1 therapy has demonstrated promising efficacy in metastatic and resectable disease. In this review, the authors discuss landmark clinical trials, highlight challenges and opportunities in this field, and propose potential directions for future work.
免疫检查点抑制剂正在迅速改变胃食管癌症患者的治疗方式。特别是，抗 PD-1 治疗在转移性和可切除疾病中显示出了有希望的疗效。在这篇综述中，作者讨论了具有里程碑意义的临床试验，强调了该领域的挑战和机遇，并提出了未来工作的潜在方向。
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