Bai Hua, He Na, Zhang Yan, Ahmad Aqsa, Yang Xing-Xing, Ma Yan, Liang Li-Jun
Department of Pediatrics, General Hospital of Ningxia Medical University, Yinchuan, 750004, People's Republic of China.
PKUFH-NINGXIA Women Children's Hospital, Yinchuan, 750001, People's Republic of China.
Diabetes Metab Syndr Obes. 2024 Mar 12;17:1267-1278. doi: 10.2147/DMSO.S446387. eCollection 2024.
In this study, we aimed to evaluate the current status of the quality of life (QOL) of pediatric patients and plasma glucose concentration regulation in children with type 1 diabetes (T1DM) in the Ningxia Hui autonomous region.
The study involved children with T1DM admitted to the General Hospital of Ningxia Medical University between October 2011 and October 2021. The children and their parents completed general information and quality of life (QOL) questionnaires. The regulation of plasma glucose concentration was assessed based on HbA1c levels, and plasma glucose and QOL-influencing components were investigated.
Among the 136 pediatric patients diagnosed with T1DM, the mean glycated hemoglobin (HbA1c) level was recorded at 8.7% (7.2%, 10.5%). A breakdown of the patient cohort revealed that 44 patients (32.4%) demonstrated good regulation of plasma glucose, 33 patients (24.3%) exhibited acceptable glycemic control, and 59 patients (43.3%) displayed poor regulation of plasma glucose. The control of plasma glucose in pediatric patients diagnosed with T1DM was affected by the duration of the disease, the patient's age, the frequency of daily plasma glucose measurements, the use of CGM, diabetic ketoacidosis (DKA), and the education level of the mother. The control of plasma glucose, dietary management, DKA, the ability to learn, and health education are interfering factors of quality of life in children diagnosed with T1DM. Effective control of plasma glucose may ensure the QOL in children with T1DM, and DKA was the risk factor for QOL.
In Ningxia, the regulation of plasma glucose in pediatric and adolescent patients with T1DM remains suboptimal, leading to poor QOL. There is a pressing need to enhance glucose regulation and QOL through comprehensive strategies, which include reinforced dietary management, rigorous monitoring of plasma glucose levels, and heightened health education levels.
在本研究中，我们旨在评估宁夏回族自治区1型糖尿病（T1DM）患儿的生活质量（QOL）现状以及血糖浓度调节情况。
该研究纳入了2011年10月至2021年10月期间在宁夏医科大学总医院收治的T1DM患儿。患儿及其家长完成了一般信息和生活质量（QOL）问卷。基于糖化血红蛋白（HbA1c）水平评估血糖浓度调节情况，并对血糖及影响生活质量的因素进行调查。
在136例诊断为T1DM的儿科患者中，糖化血红蛋白（HbA1c）平均水平记录为8.7%（7.2%，10.5%）。患者队列分析显示，44例患者（32.4%）血糖调节良好，33例患者（24.3%）血糖控制尚可，59例患者（43.3%）血糖调节不佳。诊断为T1DM的儿科患者的血糖控制受疾病病程、患者年龄、每日血糖测量频率、持续葡萄糖监测（CGM）的使用、糖尿病酮症酸中毒（DKA）以及母亲的教育水平影响。血糖控制、饮食管理、DKA、学习能力和健康教育是诊断为T1DM的儿童生活质量的干扰因素。有效控制血糖可确保T1DM患儿的生活质量，而DKA是影响生活质量的危险因素。
在宁夏，T1DM儿童和青少年患者的血糖调节仍不理想，导致生活质量较差。迫切需要通过综合策略加强血糖调节和提高生活质量，这些策略包括强化饮食管理、严格监测血糖水平以及提高健康教育水平。
