The School of Medicine, Nankai University, Tianjin, China; Department of Neurosurgery, The General Hospital of People's Liberation Army, Beijing, China.
Department of Pathology, The General Hospital of People's Liberation Army, Beijing, China.
World Neurosurg. 2024 May;185:e1280-e1286. doi: 10.1016/j.wneu.2024.03.070. Epub 2024 Mar 19.
Intramedullary schwannoma is a relatively rare tumor with only a few literature reports. This study was aimed to report the clinical characteristics of intramedullary schwannoma and discuss imaging findings and treatment strategies.
The inclusion criterion was consecutive patients with intramedullary schwannomas who were surgically treated in our institution between 2017 and 2022. Data included clinical characteristics, radiologic features, surgical management, and prognosis. Clinical and follow-up details of all cases were collected and reviewed.
This study included 3 male and 8 female patients. The mean age was 45 years (range 26-77 years). Cervical spine (4 cases, 36.4%), thoracic spine (4 cases, 36.4%), and lumbosacral spine (3 cases, 27.3%) involvement was found. Weakness, numbness and pain of limbs were the main symptoms at administration. Preoperative magnetic resonance imaging demonstrated lesion with spinal cord medullary invasion and well demarcated margins. The postoperative histologic examination showed benign lesions and confirmed the schwannoma.
This article presented a series of 11 cases of intramedullary schwannoma with sharp margins and well-enhanced features. Prognosis and functional recovery were good after gross total resection.
髓内神经鞘瘤是一种相对罕见的肿瘤，仅有少数文献报道。本研究旨在报告髓内神经鞘瘤的临床特征，并探讨其影像学表现和治疗策略。
纳入标准为 2017 年至 2022 年在我院接受手术治疗的连续髓内神经鞘瘤患者。资料包括临床特征、影像学特征、手术管理和预后。收集并回顾所有病例的临床和随访资料。
本研究纳入 3 例男性和 8 例女性患者，平均年龄 45 岁（范围 26-77 岁）。颈椎（4 例，36.4%）、胸椎（4 例，36.4%）和腰骶椎（3 例，27.3%）受累。就诊时主要症状为四肢无力、麻木和疼痛。术前磁共振成像显示病变累及脊髓髓内，边界清楚。术后组织学检查显示良性病变，证实为神经鞘瘤。
本文报道了 11 例边缘锐利、增强明显的髓内神经鞘瘤病例。大体全切除后预后和功能恢复良好。
