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巴西血液学、血液疗法与细胞疗法协会关于患者血液管理的共识:术前凝血功能的评估与管理

Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management: Assessment and management of coagulation in the preoperative period.

作者信息

Leite Flavia, Benites Bruno Deltreggia, da Silva Roberto Luiz, Soriano Selma, Alves Susankerle de Oliveira Costa, Rizzo Silvia Renata Cornélio Parolin, Rabello Guilherme, Junior Dante Mario Langhi

机构信息

Hemocentro de Ribeirão Preto, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HCFMRP-USP), Ribeirão Preto, SP, Brazil.

Centro de Hematologia e Hemoterapia da Universidade Estadual de Campinas (Hemocentro UNICAMP), Campinas, SP, Brazil.

出版信息

Hematol Transfus Cell Ther. 2024 Apr;46 Suppl 1(Suppl 1):S24-S31. doi: 10.1016/j.htct.2024.02.005. Epub 2024 Mar 13.

Abstract

Managing coagulation disorders and potential bleeding risks, especially in the context of anticoagulant medications, is of immense value both clinically and prior to surgery. Coagulation disorders can lead to bleeding complications, affecting patient safety and surgical outcomes. The use of Patient Blood Management protocols offers a comprehensive, evidence-based approach that effectively addresses these challenges. The problem is to find a delicate balance between preventing thromboembolic events (blood clots) and reducing the risk of bleeding. Anticoagulant medications, although crucial to preventing clot formation, can increase the potential for bleeding during surgical procedures. Patient blood management protocols aim to optimize patient outcomes by minimizing blood loss and unnecessary transfusions.

摘要

处理凝血障碍和潜在出血风险,尤其是在使用抗凝药物的情况下,在临床和手术前都具有巨大价值。凝血障碍可导致出血并发症,影响患者安全和手术结果。采用患者血液管理方案提供了一种全面的、基于证据的方法,可有效应对这些挑战。问题在于要在预防血栓栓塞事件(血凝块)和降低出血风险之间找到微妙的平衡。抗凝药物虽然对预防血栓形成至关重要,但会增加手术过程中出血的可能性。患者血液管理方案旨在通过尽量减少失血和不必要的输血来优化患者的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a69a/11069057/2dc2257ff38e/gr1.jpg

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