Department of Urology, Dalhousie University, Halifax, Nova Scotia, B3H 2Y9, Canada.
Division of Urology, The Hospital for Sick Children, Toronto, Ontario, M5G 1E8, Canada.
J Pediatr Urol. 2024 Jun;20(3):386-394. doi: 10.1016/j.jpurol.2024.03.007. Epub 2024 Mar 14.
Computed tomography (CT) imaging is used for assessment of pediatric urolithiasis in cases where ultrasound is inconclusive. The utility of CT imaging must be considered alongside the potential risks of radiation exposure in this patient population due to the increased risk of cancer development. The purpose of this review is to investigate the radiation exposure associated with standard-dose and low-dose computed tomography (CT) imaging for the assessment of pediatric urolithiasis.
A scoping literature review over a 23 year period between 2000 and 2023 was conducted of all English-language studies reporting on the use of non-contrast CT imaging for assessment of pediatric urolithiasis. Patients that were specified as pediatric with age ≤20 years at time of intervention and undergoing standard-dose or low/ultra-low-dose CT were included. Low-dose and ultra-low-dose CT were defined as a radiation dose ≤3.0 mSv and ≤1.9 mSv, respectively.
A total of 8121 articles were identified and after screening, 6 articles representing 309 patients were included in this scoping review. Of the articles reviewed, standard non-contrast CT radiation doses for pediatric urolithiasis evaluation ranged from 2.9 to 5.5 mSv and low-dose CT radiation dose was reported to be 1.0-2.72 mSv. Only 2 studies directly evaluated low-dose CT imaging compared to standard-dose CT imaging for pediatric urolithiasis assessment. Radiation reduction approaches did not negatively impact urolithiasis detection or characterization in 2 studies reviewed.
CT radiation doses for suspected or known pediatric urolithiasis are underreported and vary greatly with underutilization of low-dose/ultra-dose protocols for pediatric urolithiasis especially in comparison to the adult population. Results from this scoping review support that low-dose CTprotocols for pediatric stone disease are feasible to reduce radiation exposure.
计算机断层扫描(CT)成像用于评估超声检查结果不确定的小儿尿石症。由于癌症发展风险增加,在这个患者群体中,必须考虑 CT 成像的实用性以及辐射暴露的潜在风险。本综述的目的是研究评估小儿尿石症的标准剂量和低剂量 CT 成像相关的辐射暴露。
对 2000 年至 2023 年期间发表的所有关于非对比 CT 成像用于评估小儿尿石症的英文研究进行了范围界定文献回顾。纳入标准为干预时年龄≤20 岁的小儿患者,并进行标准剂量或低/超低剂量 CT 检查。低剂量和超低剂量 CT 定义为辐射剂量分别≤3.0 mSv 和≤1.9 mSv。
共确定了 8121 篇文章,经过筛选,共有 6 篇文章代表 309 例患者纳入本范围综述。回顾的文章中,小儿尿石症评估的标准非对比 CT 辐射剂量范围为 2.9 至 5.5 mSv,低剂量 CT 辐射剂量为 1.0 至 2.72 mSv。只有 2 项研究直接评估了低剂量 CT 成像与标准剂量 CT 成像在小儿尿石症评估中的比较。审查的 2 项研究中,减少辐射的方法并未对尿石症的检测或特征产生负面影响。
疑似或已知小儿尿石症的 CT 辐射剂量报告不足,且差异很大,小儿尿石症低剂量/超低剂量方案的利用率很低,与成人相比尤其如此。本范围综述的结果支持小儿结石病低剂量 CT 方案可降低辐射暴露。