Department of Orthopaedic Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, No.76 Nanguo Road, Beilin District, Xi'an, 710054, Shaanxi, China.
Sci Rep. 2024 Mar 26;14(1):7089. doi: 10.1038/s41598-024-57809-1.
The purpose of this study is to evaluate the efficacy of plate augmentation and hybrid bone grafting for treating atrophic nonunion of the femur with original intramedullary nail retained in situ.In this study, 36 patients with atrophic nonunion of the femur who underwent surgery using the technique of plate augmentation and a hybrid bone grafting while retaining the original intramedullary nail in situ in Xi'an Honghui Hospital from January 2019 to December 2021 were enrolled. 28 patients who met the inclusion and exclusion criteria were ultimately included in the study. These 28 patients, consisting of 20 males and 8 females with a mean age of 38 years, were evaluated based on factors such as operation time, intraoperative blood loss, the average hospitalization days. Additionally, the results and function of these patients were evaluated by union time, Wu's scores of limb function and incidence of serious complications.All 28 patients achieved bone union at the 12 month follow-up, with an average follow-up time of 14.6 ± 4.2 months.The average operation time was 68.3 ± 11.2 min, and the average intraoperative blood loss was 140 ± 22.6 ml. Patients were hospitalized for an average of 5.8 ± 1.1 days. Full clinical and radiological bone union was achieved on average at 5.1 ± 1.9 months. The mean value of Wu's scores at the 12 month follow-up was significantly higher than before the operation. Limb function was excellent in 27 patients and good in one patient at the 12 month follow-up. However, five patients experienced the lower limb vein thrombosis, including one deep vein thrombosis and four lower limb intermuscular vein thromboses. One patient had a superficial infections of the surgical incision site, while three patients reported pain and numbness where their iliac bone graft was extracted at the 12 month follow-up. The technique of plate augmentation and hybrid bone grafting, combined with retaining the original intramedullary nail in situ has been shown to be a safe, effective, simply and standardizable practice for treating atrophic femoral nonunion with an intact original IMN fixation.
本研究旨在评估钢板增强和混合骨移植治疗原位保留原始髓内钉的萎缩性股骨骨不连的疗效。本研究共纳入 2019 年 1 月至 2021 年 12 月在西安红会医院采用钢板增强和混合骨移植治疗同时原位保留原始髓内钉治疗萎缩性股骨骨不连的 36 例患者。最终纳入符合纳入和排除标准的 28 例患者。这 28 例患者包括 20 例男性和 8 例女性,平均年龄 38 岁,根据手术时间、术中出血量、平均住院天数等因素进行评估。此外,通过愈合时间、肢体功能 Wu 评分和严重并发症发生率评估这些患者的结果和功能。所有 28 例患者均在 12 个月随访时达到骨愈合,平均随访时间为 14.6±4.2 个月。平均手术时间为 68.3±11.2 分钟,平均术中出血量为 140±22.6ml。患者平均住院 5.8±1.1 天。平均在 5.1±1.9 个月时获得完全临床和影像学骨愈合。12 个月随访时 Wu 评分的平均值明显高于术前。12 个月随访时,27 例患者肢体功能优良,1 例患者良好。然而,5 例患者发生下肢静脉血栓形成,其中 1 例深静脉血栓形成,4 例下肢肌间静脉血栓形成。1 例患者切口浅表感染,3 例患者髂骨取骨处疼痛麻木,在 12 个月随访时报告。钢板增强和混合骨移植联合原位保留原始髓内钉固定治疗有完整原始 IMN 固定的萎缩性股骨骨不连是一种安全、有效、简单和标准化的方法。