Department of Gynecology, Portuguese Institute of Oncology of Lisbon Francisco Gentil, Lisboa, Portugal.
First Faculty of Medicine, Charles University, Prague, Czech Republic.
Int J Gynecol Cancer. 2024 Jun 3;34(6):871-878. doi: 10.1136/ijgc-2023-005264.
In addition to the diagnostic accuracy of imaging methods, patient-reported satisfaction with imaging methods is important.
To report a secondary outcome of the prospective international multicenter Imaging Study in Advanced ovArian Cancer (ISAAC Study), detailing patients' experience with abdomino-pelvic ultrasound, whole-body contrast-enhanced computed tomography (CT), and whole-body diffusion-weighted magnetic resonance imaging (WB-DWI/MRI) for pre-operative ovarian cancer work-up.
In total, 144 patients with suspected ovarian cancer at four institutions in two countries (Italy, Czech Republic) underwent ultrasound, CT, and WB-DWI/MRI for pre-operative work-up between January 2020 and November 2022. After having undergone all three examinations, the patients filled in a questionnaire evaluating their overall experience and experience in five domains: preparation before the examination, duration of examination, noise during the procedure, radiation load of CT, and surrounding space. Pain perception, examination-related patient-perceived unexpected, unpleasant, or dangerous events ('adverse events'), and preferred method were also noted.
Ultrasound was the preferred method by 49% (70/144) of responders, followed by CT (38%, 55/144), and WB-DWI/MRI (13%, 19/144) (p<0.001). The poorest experience in all domains was reported for WB-DWI/MRI, which was also associated with the largest number of patients who reported adverse events (eg, dyspnea). Patients reported higher levels of pain during the ultrasound examination than during CT and WB-DWI/MRI (p<0.001): 78% (112/144) reported no pain or mild pain, 19% (27/144) moderate pain, and 3% (5/144) reported severe pain (pain score >7 of 10) during the ultrasound examination. We did not identify any factors related to patients' preferred method.
Ultrasound was the imaging method preferred by most patients despite being associated with more pain during the examination in comparison with CT and WB-DWI/MRI.
NCT03808792.
除了影像学方法的诊断准确性外，患者对影像学方法的满意度也很重要。
报告前瞻性国际多中心卵巢癌影像学研究（ISAAC 研究）的次要结果，详细介绍患者在术前卵巢癌检查中接受腹部-盆腔超声、全身对比增强计算机断层扫描（CT）和全身扩散加权磁共振成像（WB-DWI/MRI）的体验。
共有四家机构的 144 名疑似卵巢癌患者在 2020 年 1 月至 2022 年 11 月期间接受了超声、CT 和 WB-DWI/MRI 术前检查。在接受了所有三项检查后，患者填写了一份问卷，评估他们的整体体验和五个领域的体验：检查前准备、检查持续时间、检查过程中的噪音、CT 的辐射负荷和周围空间。还记录了疼痛感知、与检查相关的患者感知的意外、不愉快或危险事件（“不良事件”）以及首选方法。
49%（70/144）的应答者首选超声，其次是 CT（38%，55/144）和 WB-DWI/MRI（13%，19/144）（p<0.001）。在所有领域，WB-DWI/MRI 的体验最差，与之相关的不良事件报告也最多（例如呼吸困难）。与 CT 和 WB-DWI/MRI 相比，患者在超声检查中报告的疼痛水平更高（p<0.001）：144 名患者中有 78%（112/144）报告无疼痛或轻度疼痛，19%（27/144）报告中度疼痛，3%（5/144）报告严重疼痛（疼痛评分>10 分中的 7 分）。我们没有发现任何与患者首选方法相关的因素。
尽管与 CT 和 WB-DWI/MRI 相比，超声检查在检查过程中会引起更多疼痛，但大多数患者还是选择了超声检查。
NCT03808792。
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