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光感对创伤性视神经病变患者视觉功能恢复的影响。

Effects of light perception on visual function recovery in patients with traumatic optic neuropathy.

机构信息

Department of Neurosurgery, Seventh People's Hospital Affiliated to Shanghai University of TCM, Shanghai, China.

Neurosurgery Department of the First Affiliated Hospital of Soochow University, Suzhou, China.

出版信息

Sci Rep. 2024 Mar 29;14(1):7514. doi: 10.1038/s41598-024-54324-1.

Abstract

This study aimed to assess the impact of light perception presence or absence on visual function recovery in patients with traumatic optic neuropathy (TON). A retrospective analysis was conducted on the clinical data of 206 TON patients. Based on the presence or absence of light perception after injury, patients were categorized into a light perception group and a non-light perception group. A comparison was made between the two groups regarding visual acuity recovery before and after treatment. The non-light perception group comprised 63 patients, with a treatment effectiveness rate of 39.68%. The light perception group consisted of 143 patients, with a treatment effectiveness rate of 74.83%. The difference between the two groups was statistically significant (χ = 23.464, P < 0.01). Subgroup analysis indicated that surgical treatment appeared to be more effective than steroid hormone therapy for patients with light perception. Conversely, for patients without light perception, there was no significant difference in the effectiveness of the two methods. The total effectiveness rate of the light perception group was significantly higher than that of the non-light perception group, suggesting that patients with light perception before treatment experience better outcomes compared to those without light perception. Treatment choices should be individualized to ensure optimal results.

摘要

本研究旨在评估外伤性视神经病变(TON)患者光感存在与否对视觉功能恢复的影响。对 206 例 TON 患者的临床资料进行回顾性分析。根据损伤后光感的存在与否,将患者分为光感组和无光感组。比较两组患者治疗前后视力恢复情况。无光感组 63 例,治疗有效率为 39.68%。光感组 143 例,治疗有效率为 74.83%。两组差异有统计学意义(χ=23.464,P<0.01)。亚组分析显示,手术治疗对光感患者似乎比类固醇激素治疗更有效。相反,对于无光感的患者,两种方法的有效性无显著差异。光感组的总有效率明显高于无光感组,提示治疗前有光感的患者比无光感的患者预后更好。治疗选择应个体化,以确保最佳效果。

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