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感染性角膜炎伴发眼部急性水肿的病例报告

Development of acute hydrops in eye with infectious keratitis: A case report.

作者信息

Kashima Yuzen, Kato Kumiko, Takeuchi Maki, Yonekawa Yuka, Takashima Yuko, Hirano Koji, Kondo Mineo

机构信息

Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.

Department of Ophthalmology, Matsusaka Municipal Hospital, Matsusaka, Japan.

出版信息

Am J Ophthalmol Case Rep. 2024 Mar 21;34:102045. doi: 10.1016/j.ajoc.2024.102045. eCollection 2024 Jun.

Abstract

PURPOSE

To determine the characteristics of an eye that developed acute hydrops while being treated for infectious keratitis.

OBSERVATION

A 35-year-old man presented with pain and blurred vision in his left eye. He had undergone cataract surgery seven years earlier and was being treated for poorly controlled atopic dermatitis. The decimal best-corrected visual acuity (BCVA) of the left eye was 0.01. Slit-lamp microscopy showed conjunctival injection, corneal opacification, and a corneal ulcer. The patient was diagnosed with infectious keratitis and was treated with topical and systemic antibiotics. During the hospitalization, the patient was noted to rub his eyes frequently and vigorously. Five days after the first visit, the cornea protruded markedly, and the stroma surrounding the ulcerated area was edematous. These findings led to a diagnosis of acute hydrops.Penetrating keratoplasty was performed to prevent corneal perforation. Histopathological study of the excised cornea showed stromal edema, infiltration of leukocytes, and a tear in Descemet's membrane. Unfortunately, the patient developed endophthalmitis the day after the surgery. The anterior chamber was irrigated with antibiotics, and antibiotics were also injected into the vitreous. The endophthalmitis gradually subsided, and two years after the surgery, the patient's decimal BCVA had improved to 0.6.

CONCLUSION AND IMPORTANCE

Vigorous eye rubbing in cases of infectious keratitis can induce acute hydrops, and timely surgical intervention is recommended.

摘要

目的

确定在治疗感染性角膜炎期间发生急性角膜水肿的眼睛的特征。

观察

一名35岁男性左眼出现疼痛和视力模糊。他七年前接受了白内障手术,当时正在治疗控制不佳的特应性皮炎。左眼的小数最佳矫正视力(BCVA)为0.01。裂隙灯显微镜检查显示结膜充血、角膜混浊和角膜溃疡。患者被诊断为感染性角膜炎,并接受了局部和全身抗生素治疗。住院期间,注意到患者频繁且用力地揉眼。首次就诊五天后,角膜明显突出,溃疡区域周围的基质水肿。这些发现导致诊断为急性角膜水肿。为防止角膜穿孔进行了穿透性角膜移植术。对切除的角膜进行组织病理学研究显示基质水肿、白细胞浸润和后弹力层撕裂。不幸的是,患者在手术后第二天发生了眼内炎。用抗生素冲洗前房,并将抗生素注入玻璃体。眼内炎逐渐消退,手术后两年,患者的小数BCVA提高到了0.6。

结论与意义

感染性角膜炎患者用力揉眼可诱发急性角膜水肿,建议及时进行手术干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbf/10979013/4ba92df029f4/gr1.jpg

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