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一名患有颅骨下陷综合征患者颅骨修补术后的脑实质内出血

Intraparenchymal Hemorrhage after Cranioplasty in a Patient with Sinking Flap Syndrome.

作者信息

Dos Santos Junior Romildo Antonio, Mesquita Filho Paulo Moacir, Padua Wagner Lazaretto, Martio Artur Eduardo, Bigolin Tomas Rodrigues

机构信息

ATITUS, Passo Fundo, Brazil.

Neurosurgery Department, Hospital de Clnicas de Passo Fundo, Passo Fundo, Brazil.

出版信息

Curr Health Sci J. 2023 Oct-Dec;49(4):594-596. doi: 10.12865/CHSJ.49.04.16. Epub 2023 Dec 29.

Abstract

Decompressive craniectomy has been increasingly used in recent decades for the treatment of uncontrollable intracranial hypertension caused by trauma, malignant strokes, cerebral venous thrombosis, among others. Sinking flap syndrome (SFS) is a rare complication characterized by neurological deterioration after craniectomy. Here, we report the case of a 73-year-old female patient who presented with disorientation, lip rhyme deviation to the right and left hemiparesis after cardiac catheterization. In view of the presence of a malignant stroke, as well as the willingness of the family members to make a total investment to save the patient's life, decompressive hemicraniectomy was indicated. Subsequently, due to occasional headache attacks, nausea and vomiting, in addition to progressive depression of the subcutaneous flap, the possibility of SFS was suggested and cranioplasty was indicated, which occurred without perioperative intercurrences. Although the patient maintained a stable neurological status, a post-surgical computed tomography (CT) scan of the head showed a right intraparenchymal hemorrhagic lesion, associated with parenchymal expansion and midline deviation. To the best of our knowledge, intraparenchymal hemorrhages are not common complications after performing cranioplasty, and additional studies are needed to understand the reasons why this occurs. The mechanisms responsible for this type of injury are not well understood, but involve reperfusion damage and loss of brain compliance. Despite representing an uncommon complication, post-cranioplasty hemorrhage can cause severe morbidity to the patient, and early diagnosis and intervention are of great importance in these cases.

摘要

近几十年来,减压性颅骨切除术越来越多地用于治疗由创伤、恶性中风、脑静脉血栓形成等引起的无法控制的颅内高压。下沉皮瓣综合征(SFS)是一种罕见的并发症,其特征为颅骨切除术后神经功能恶化。在此,我们报告一例73岁女性患者,该患者在心脏导管插入术后出现定向障碍、口角向右侧偏斜及左侧偏瘫。鉴于存在恶性中风,以及家属愿意全力投资挽救患者生命,遂行减压性半颅骨切除术。随后,由于患者偶尔出现头痛发作、恶心和呕吐,除皮下皮瓣逐渐凹陷外,提示可能为SFS,并建议行颅骨成形术,手术过程中未发生围手术期并发症。尽管患者神经状态保持稳定,但术后头部计算机断层扫描(CT)显示右侧脑实质内出血性病变,伴有脑实质扩张和中线偏移。据我们所知,脑实质内出血并非颅骨成形术后的常见并发症,需要进一步研究以了解其发生原因。导致此类损伤的机制尚不完全清楚,但涉及再灌注损伤和脑顺应性丧失。尽管颅骨成形术后出血是一种罕见的并发症,但可导致患者严重发病,并在这些病例中早期诊断和干预非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2824/10976200/f872e371303e/CHSJ-49-04-594-fig1.jpg

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本文引用的文献

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One case report of delayed severe intracerebral and intraventricular hemorrhage after cranioplasty.
Br J Neurosurg. 2024 Apr;38(2):536-539. doi: 10.1080/02688697.2020.1859093. Epub 2020 Dec 11.
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