口腔扁平苔藓用乌帕替尼治疗后得到改善。

Oral Lichen Planus Successfully Treated With Upadacitinib.

出版信息

J Drugs Dermatol. 2024 Apr 1;23(4):e104-e106. doi: 10.36849/JDD.7859.

Abstract

With the rise of Janus kinase (JAK) and Signal Transducer and Activator of Transcription (STAT) inhibitor use in dermatologic conditions, there has been increasing hope in treating extensive and difficult-to-treat inflammatory cutaneous conditions. Today we report a case of oral lichen planus successfully treated with an oral JAK1 inhibitor, upadacitinib. This case had been unresponsive by several standard methods but responded with 70% improvement within 1 month when treated with upadacitinib. J Drugs Dermatol. 2024;23(4):7859. doi:10.36849/JDD.7859e &nbsp.

摘要

随着 Janus 激酶（JAK）和信号转导与转录激活因子（STAT）抑制剂在皮肤科疾病中的应用增加，人们越来越希望能够治疗广泛且难以治疗的炎症性皮肤疾病。今天，我们报告了一例成功使用口服 JAK1 抑制剂乌帕替尼治疗的口腔扁平苔藓病例。该病例对几种标准方法均无反应，但在使用乌帕替尼治疗 1 个月内，病情改善了 70%。J 皮肤病学杂志。2024；23（4）：7859。doi:10.36849/JDD.7859e 。