Paz-López Alexis Jared, Rafael-Pérez Carlos Ignacio, Llanos-Salas Brenda Aurora, Castañeda-Anaya Paola Saskia, Gómez-Arenas Samuel Rodrigo, Nacud-Bezies Yamir Ahmed
Departamento de cirugía digestiva y endocrina, Unidad Médica de Alta Especialidad No. 25, Monterrey, MEX.
Cureus. 2024 Mar 4;16(3):e55504. doi: 10.7759/cureus.55504. eCollection 2024 Mar.
Pheochromocytomas are neuroendocrine tumors that produce, store, and secrete catecholamines. They are found in the chromaffin tissue of the adrenal medulla and manifest clinical symptoms by producing an excessive amount of one or more catecholamines, such as dopamine, adrenaline, and noradrenaline, as well as their inactive metabolites, such as metanephrine, normetanephrine, and 3-methoxytyramine. This paper is the case report of a 53-year-old male patient with diabetes and hypertension who has been experiencing symptoms such as night sweats, frequent colds, weight loss, reduced appetite, and generalized anxiety. The patient presented with pelvic pain and sought medical attention, leading to an abdominal MRI scan that revealed a right adrenal mass. The patient's plasma metanephrine levels were found to be four-fold higher than the normal range. A contrast CT scan of the abdomen and pelvis revealed a right adrenal gland with increased dimensions and well-defined edges. A diagnosis of right adrenal pheochromocytoma was made. The patient underwent a right laparoscopic adrenalectomy, which resulted in a reduction in metanephrine levels and normal blood pressure readings. The patient presented a favorable clinical evolution in the post-surgical period, for which it was decided to be discharged home.
嗜铬细胞瘤是一种能产生、储存和分泌儿茶酚胺的神经内分泌肿瘤。它们存在于肾上腺髓质的嗜铬组织中,通过产生过量的一种或多种儿茶酚胺(如多巴胺、肾上腺素和去甲肾上腺素)及其无活性代谢产物(如间甲肾上腺素、去甲间甲肾上腺素和3-甲氧基酪胺)而表现出临床症状。本文是一例53岁男性糖尿病和高血压患者的病例报告,该患者一直有盗汗、频繁感冒、体重减轻、食欲减退和广泛性焦虑等症状。患者因盆腔疼痛就医,腹部MRI扫描显示右肾上腺有肿块。发现患者血浆间甲肾上腺素水平比正常范围高四倍。腹部和盆腔增强CT扫描显示右肾上腺体积增大且边缘清晰。诊断为右肾上腺嗜铬细胞瘤。患者接受了右侧腹腔镜肾上腺切除术,术后间甲肾上腺素水平降低,血压读数恢复正常。患者术后临床进展良好,因此决定出院回家。